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前列腺水刀消融术:综述与更新

Aquablation of the prostate: a review and update.

作者信息

Roehrborn Claus G, Teplitsky Seth, Das Akhil K

机构信息

Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

出版信息

Can J Urol. 2019 Aug;26(4 Suppl 1):20-24.

PMID:31481145
Abstract

INTRODUCTION

Invasive procedures, such as transurethral resection of the prostate (TURP), have long been the gold standard therapy for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). In recent years, newer treatment modalities have arisen, such as Aquablation, with similar efficacy and improved adverse event profiles, with particular emphasis on postoperative sexual function.

MATERIALS AND METHODS

Aquablation is a new technology that utilizes machine-controlled water jets to ablate the soft tissue of the prostate as determined by the doctor. In this review, we will discuss the techniques currently being used to complete this procedure, the outcomes and safety, and finally, the long term data as well as the adverse events associated with Aquablation.

RESULTS

Aquablation is rapidly effective in treating patients with LUTS due to BPH. Critically, in head to head comparison with TURP, Aquablation has equivalent objective results with much shorter resections times, and significantly less sexual side effects. Currently, the literature only reports results extending to 12 months post-procedure, and therefore long term durability of results beyond this time point remains unknown.

CONCLUSIONS

Aquablation is a safe and effective option for treating LUTS secondary to BPH. Aquablation is a new surgical option that shows very promising short term results, in particular, due to its short resection time regardless of gland size and low rate of sexual side effects. This technology still requires further investigation to confirm durability and efficacy over time.

摘要

引言

侵入性手术,如经尿道前列腺切除术(TURP),长期以来一直是治疗良性前列腺增生(BPH)继发下尿路症状(LUTS)的金标准疗法。近年来,出现了更新的治疗方式,如水刀汽化术,其疗效相似且不良事件谱有所改善,尤其强调术后性功能。

材料与方法

水刀汽化术是一种利用机器控制的水射流来消融医生所确定的前列腺软组织的新技术。在本综述中,我们将讨论目前用于完成该手术的技术、结果和安全性,最后讨论长期数据以及与水刀汽化术相关的不良事件。

结果

水刀汽化术在治疗BPH所致LUTS患者方面迅速有效。至关重要的是,与TURP进行直接比较时,水刀汽化术的客观结果相当,但切除时间短得多,且性副作用明显更少。目前,文献仅报道了术后12个月的结果,因此超过该时间点的长期疗效仍不清楚。

结论

水刀汽化术是治疗BPH继发LUTS的一种安全有效的选择。水刀汽化术是一种新的手术选择,其短期结果非常有前景,特别是因其切除时间短,与腺体大小无关,且性副作用发生率低。该技术仍需进一步研究以确认其长期疗效和有效性。

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Aquablation of the prostate: a review and update.前列腺水刀消融术:综述与更新
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