Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon.
Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon.
J Mycol Med. 2019 Dec;29(4):317-319. doi: 10.1016/j.mycmed.2019.100895. Epub 2019 Aug 27.
Vulvovaginal candidiasis (VVC) is one of the most common lower genital tract infections in women; this unpleasant and extremely embarrassing pathology is one of the main reasons for gynaecological consultation. In Gabon, the prevalence of VVC remains poorly described even though VVC is known to be the leading gynaecological condition in several countries. This retrospective cross-sectional study sought to assess the prevalence of VVC among symptomatic women in southeastern Gabon.
Clinical samples were collected from patients suspected to have VVC during a 2-year period (from January 2016 to December 2017). Gram staining of vaginal smears provided indications of vaginal flora and confirmed the presence of yeast. Sabouraud-chloramphenicol and chromID Candida media were used to isolate yeast, and species identification was performed using morphological tests and the Vitek 2 Compact automated system.
For the 873 patients included in this study, the prevalence of VVC was 28.52%. Eleven Candida species were identified, with greater representation of Candidaalbicans (82.73%) than of Non C. albicanscandida (NCAC) (17.27%), which were distributed as follows: Candidafamata (4.02%), Candida spp. (3.61%), Candidarugosa (3.21%), Candidalipolytica (1.61%), Candidaparapsilosis (1.61%), Candidaglabrata (1.21%), Candidatropicalis (0.80%), Candidakrusei (0.40%), Candidadubliniensis (0.40%), and Candidasphaerica (0.40%).
This study offers the first estimation of VVC among Gabonese women in childbearing age with the symptoms. It showed that VVC is very common in Gabon. C. albicans as the most commonly represented species.
外阴阴道假丝酵母菌病（VVC）是女性下生殖道最常见的感染之一；这种令人不快且极其尴尬的疾病是妇科就诊的主要原因之一。在加蓬，VVC 的患病率描述得仍不够完善，尽管 VVC 已知是一些国家主要的妇科疾病。这项回顾性横断面研究旨在评估加蓬东南部有症状的女性中 VVC 的患病率。
在 2 年期间（2016 年 1 月至 2017 年 12 月），从疑似患有 VVC 的患者中采集临床样本。阴道涂片的革兰氏染色提供了阴道菌群的指示，并确认了酵母的存在。使用沙保弱氯苯醇和 chromID Candida 培养基分离酵母，使用形态学试验和 Vitek 2 Compact 自动化系统进行种属鉴定。
在这项研究中，873 例患者中 VVC 的患病率为 28.52%。鉴定出 11 种假丝酵母菌，C. albicans 的代表性大于非 C. albicans 假丝酵母菌（NCAC）（82.73%对 17.27%），分布如下：Candidafamata（4.02%）、Candida spp.（3.61%）、Candidarugosa（3.21%）、Candidalipolytica（1.61%）、Candidaparapsilosis（1.61%）、Candidaglabrata（1.21%）、Candidatropicalis（0.80%）、Candidakrusei（0.40%）、Candidadubliniensis（0.40%）和 Candidasphaerica（0.40%）。
这项研究提供了加蓬育龄期有症状妇女中 VVC 的首次估计。结果表明，VVC 在加蓬非常常见，最常见的代表菌种是 C. albicans。
