[Spinal mechanism of the antispastic action of TRH in patients with amyotrophic lateral sclerosis].
作者信息
Morin C, Pierrot-Deseilligny E
机构信息
Laboratoire de Neurophysiologie Clinique, Hôpital de la Salpêtrière, Paris.
出版信息
Rev Neurol (Paris). 1988;144(11):701-3.
PMID:3148185
Abstract
Effects of high-dose TRH on the vibratory inhibition of soleus H-reflex have been studied in 9 patients with amyotrophic lateral sclerosis. In 6 of the 9, TRH induced a significant increase in vibratory inhibition. This suggests that the TRH-induced reduction of spasticity might be due to an increase in presynaptic inhibition acting on Ia fibres.
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