Morin C, Pierrot-Deseilligny E
Laboratoire de Neurophysiologie Clinique, Hôpital de la Salpêtrière, Paris.
Rev Neurol (Paris). 1988;144(11):701-3.
Effects of high-dose TRH on the vibratory inhibition of soleus H-reflex have been studied in 9 patients with amyotrophic lateral sclerosis. In 6 of the 9, TRH induced a significant increase in vibratory inhibition. This suggests that the TRH-induced reduction of spasticity might be due to an increase in presynaptic inhibition acting on Ia fibres.
