• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

无菌性脑膜炎与抑郁:一例系统性红斑狼疮患者的神经精神表现

Aseptic Meningitis and Depression: The Neuropsychiatric Manifestations of a Patient with Systemic Lupus Erythematosus.

作者信息

Irby Ivania T, Leja Patrycia, Manning Donald, Limaye Kaustubh, Lahoti Sourabh

机构信息

Psychiatry, Coliseum Medical Center, Macon, USA.

Miscellaneous, Carl Vinson Veterans Affairs Medical Center, Dublin, USA.

出版信息

Cureus. 2019 Aug 19;11(8):e5424. doi: 10.7759/cureus.5424.

DOI:10.7759/cureus.5424
PMID:31482046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6701903/
Abstract

Aseptic meningitis as an initial and isolated manifestation of systemic lupus erythematosus (SLE) is extremely rare. About a third of patients with SLE have neuropsychiatric manifestations; however, less than 2% develop aseptic meningitis. Therefore, SLE as a cause of aseptic meningitis is commonly overlooked and leads to delayed or even missed diagnosis. We report a case of aseptic meningitis that was later discovered to be SLE and where instituting appropriate treatment led to clinical improvement.

摘要

无菌性脑膜炎作为系统性红斑狼疮(SLE)的首发及孤立表现极为罕见。约三分之一的SLE患者有神经精神表现;然而,不到2%的患者会发展为无菌性脑膜炎。因此,SLE作为无菌性脑膜炎的病因常被忽视,导致诊断延迟甚至漏诊。我们报告一例无菌性脑膜炎病例,该病例后来被发现是SLE,经采取适当治疗后临床症状改善。

相似文献

1
Aseptic Meningitis and Depression: The Neuropsychiatric Manifestations of a Patient with Systemic Lupus Erythematosus.无菌性脑膜炎与抑郁:一例系统性红斑狼疮患者的神经精神表现
Cureus. 2019 Aug 19;11(8):e5424. doi: 10.7759/cureus.5424.
2
Aseptic meningitis as initial manifestation of systemic lupus erythematosus: Case series.无菌性脑膜炎作为系统性红斑狼疮的初始表现:病例系列
Lupus. 2022 Mar;31(3):373-377. doi: 10.1177/09612033221078213. Epub 2022 Feb 8.
3
Aseptic meningitis in systemic lupus erythematosus. Report of three cases.系统性红斑狼疮中的无菌性脑膜炎。三例报告。
Arthritis Rheum. 1975 Jul-Aug;18(4):369-74. doi: 10.1002/art.1780180414.
4
Utility of TWEAK to assess neuropsychiatric disease activity in systemic lupus erhytematosus.TWEAK用于评估系统性红斑狼疮神经精神疾病活动度的效用。
Lupus. 2016 Apr;25(4):364-9. doi: 10.1177/0961203315610206. Epub 2015 Oct 13.
5
Association of anti-triosephosphate isomerase antibodies with aseptic meningitis in patients with neuropsychiatric systemic lupus erythematosus.抗磷酸丙糖异构酶抗体与神经精神性系统性红斑狼疮患者无菌性脑膜炎的关联
Clin Rheumatol. 2017 Jul;36(7):1655-1659. doi: 10.1007/s10067-017-3653-2. Epub 2017 Apr 28.
6
Recurrent benign lymphocytic (mollaret) meningitis in systemic lupus erythematosus.系统性红斑狼疮中的复发性良性淋巴细胞性(莫拉雷)脑膜炎。
Neurologist. 2008 Jan;14(1):43-5. doi: 10.1097/NRL.0b013e318157a669.
7
Meningitis as the initial manifestation of systemic lupus erythematosus.脑膜炎作为系统性红斑狼疮的首发表现。
IDCases. 2020 Jul 4;21:e00904. doi: 10.1016/j.idcr.2020.e00904. eCollection 2020.
8
Differences between central nervous system infection and neuropsychiatric systemic lupus erythematosus in patients with systemic lupus erythematosus.系统性红斑狼疮患者中枢神经系统感染与神经精神性系统性红斑狼疮的差异。
J Int Med Res. 2018 Jan;46(1):485-491. doi: 10.1177/0300060517722695. Epub 2017 Aug 21.
9
Clinical features of central nervous system infections and experience in differential diagnosis from neuropsychiatric lupus erythematosus in a cohort of 8491 patients with systemic lupus erythematosus.8491 例系统性红斑狼疮患者中枢神经系统感染的临床特征及与神经精神狼疮鉴别诊断的经验。
Arthritis Res Ther. 2019 Aug 19;21(1):189. doi: 10.1186/s13075-019-1971-2.
10
Serum and cerebrospinal fluid autoantibodies in patients with neuropsychiatric lupus erythematosus. Implications for diagnosis and pathogenesis.神经精神性红斑狼疮患者的血清和脑脊液自身抗体。对诊断和发病机制的意义。
PLoS One. 2008 Oct 6;3(10):e3347. doi: 10.1371/journal.pone.0003347.

引用本文的文献

1
Neuropsychiatric lupus or West Nile encephalitis? Diagnostic dilemmas in two SLE patients and literature review.神经精神性狼疮还是西尼罗河脑炎?两名系统性红斑狼疮患者的诊断困境及文献综述
Intern Emerg Med. 2025 Jun 4. doi: 10.1007/s11739-025-03993-5.
2
Nuclear receptors modulate inflammasomes in the pathophysiology and treatment of major depressive disorder.核受体在重度抑郁症的病理生理学和治疗中调节炎性小体。
World J Psychiatry. 2021 Dec 19;11(12):1191-1205. doi: 10.5498/wjp.v11.i12.1191.

本文引用的文献

1
The blood brain barrier and neuropsychiatric lupus: new perspectives in light of advances in understanding the neuroimmune interface.血脑屏障与神经精神性狼疮:基于对神经免疫界面理解进展的新观点
Autoimmun Rev. 2017 Jun;16(6):612-619. doi: 10.1016/j.autrev.2017.04.008. Epub 2017 Apr 17.
2
Neuropsychiatric lupus: a mosaic of clinical presentations.神经精神性狼疮:临床表现的拼图。
BMC Med. 2015 Mar 4;13:43. doi: 10.1186/s12916-015-0269-8.
3
Neuropsychiatric systemic lupus erythematosus.神经精神性狼疮。
Curr Neuropharmacol. 2011 Sep;9(3):449-57. doi: 10.2174/157015911796557984.
4
Neuropsychiatric syndromes in systemic lupus erythematosus: a meta-analysis.神经精神性狼疮的神经精神性综合征:一项荟萃分析。
Semin Arthritis Rheum. 2011 Aug;41(1):1-11. doi: 10.1016/j.semarthrit.2010.08.001. Epub 2010 Oct 20.
5
EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs.EULAR 推荐的伴有神经精神表现的系统性红斑狼疮的管理:EULAR 常务委员会临床事务工作组的报告。
Ann Rheum Dis. 2010 Dec;69(12):2074-82. doi: 10.1136/ard.2010.130476. Epub 2010 Aug 19.
6
Neuropsychiatric events at the time of diagnosis of systemic lupus erythematosus: an international inception cohort study.系统性红斑狼疮诊断时的神经精神事件:一项国际初始队列研究。
Arthritis Rheum. 2007 Jan;56(1):265-73. doi: 10.1002/art.22305.
7
The central nervous system in systemic lupus erythematosus. Part 1. Clinical syndromes: a literature investigation.系统性红斑狼疮中的中枢神经系统。第1部分。临床综合征:文献调查。
Rheumatology (Oxford). 2002 Jun;41(6):605-18. doi: 10.1093/rheumatology/41.6.605.
8
The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes.美国风湿病学会关于神经精神性狼疮综合征的命名和病例定义。
Arthritis Rheum. 1999 Apr;42(4):599-608. doi: 10.1002/1529-0131(199904)42:4<599::AID-ANR2>3.0.CO;2-F.
9
Aseptic meningitis in systemic lupus erythematosus. Report of three cases.系统性红斑狼疮中的无菌性脑膜炎。三例报告。
Arthritis Rheum. 1975 Jul-Aug;18(4):369-74. doi: 10.1002/art.1780180414.