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本文引用的文献

1
Chronic meningitis in systemic lupus erythematosus: An unusual etiology.系统性红斑狼疮中的慢性脑膜炎：一种不寻常的病因。
Ann Indian Acad Neurol. 2014 Oct;17(4):426-8. doi: 10.4103/0972-2327.144019.
2
Understanding the epidemiology and progression of systemic lupus erythematosus.了解系统性红斑狼疮的流行病学和进展。
Semin Arthritis Rheum. 2010 Feb;39(4):257-68. doi: 10.1016/j.semarthrit.2008.10.007. Epub 2009 Jan 10.
3
Clinical characteristics and outcomes of the meningitides in systemic lupus erythematosus.系统性红斑狼疮中脑膜炎的临床特征与结局
Eur Neurol. 2009;61(3):143-8. doi: 10.1159/000186504. Epub 2008 Dec 18.
4
Chronic meningitis: still a diagnostic challenge.慢性脑膜炎：仍然是一个诊断难题。
J Neurol. 2003 Jun;250(6):653-60. doi: 10.1007/s00415-003-1101-5.
5
Neuropsychiatric manifestations in Thai patients with systemic lupus erythematosus.泰国系统性红斑狼疮患者的神经精神表现
Asian Pac J Allergy Immunol. 2002 Sep;20(3):179-85.
6
Chronic meningitis without predisposing illness--a review of 83 cases.无易感疾病的慢性脑膜炎——83例病例回顾
Q J Med. 1987 Apr;63(240):283-95.
7
The incidence and prognosis of central nervous system disease in systemic lupus erythematosus.系统性红斑狼疮中枢神经系统疾病的发病率及预后
J Rheumatol. 1992 Jan;19(1):47-52.

脑膜炎作为系统性红斑狼疮的首发表现。

Meningitis as the initial manifestation of systemic lupus erythematosus.

作者信息

Al Mahmeed Nada, El Nekidy Wasim S, Langah Rumman, Nusair Ahmad Rakad

机构信息

Medical Subspecialties Institute- Department of Hospital Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

Department of Pharmacy Services, Cleveland Clinic Abu Dhabi, P. O. Box 112412, Abu Dhabi, United Arab Emirates.

出版信息

IDCases. 2020 Jul 4;21:e00904. doi: 10.1016/j.idcr.2020.e00904. eCollection 2020.

DOI:10.1016/j.idcr.2020.e00904
PMID:32695609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7364116/
Abstract

Systemic Lupus Erythematosus (SLE) is an idiopathic chronic autoimmune disease that can affect multiple organs including the Central Nervous System (CNS). CNS involvement is seen in many SLE patients; however, usually it is preceded by/or in conjunction with other organ-system involvement. The spectrum of CNS involvement is wide and includes numerous neuro-psychiatric syndromes but rarely meningitis. Even when meningitis occurs it is almost never the presenting manifestation of SLE. Our case had chronic aseptic meningitis as the initial and seemingly sole manifestation of SLE, which was erroneously, treated as tuberculous (TB) meningitis.

摘要

系统性红斑狼疮（SLE）是一种特发性慢性自身免疫性疾病，可累及包括中枢神经系统（CNS）在内的多个器官。许多SLE患者会出现中枢神经系统受累；然而，通常在此之前或同时伴有其他器官系统受累。中枢神经系统受累的范围很广，包括众多神经精神综合征，但很少出现脑膜炎。即使发生脑膜炎，它几乎从未作为SLE的首发表现。我们的病例以慢性无菌性脑膜炎作为SLE的初始且似乎唯一的表现，曾被错误地当作结核性（TB）脑膜炎进行治疗。