Department of Sciences, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy.
Molecules. 2019 Sep 3;24(17):3193. doi: 10.3390/molecules24173193.
A novel synthetic strategy for obtainment of (±)-3-deoxyradicinin () is reported. This synthetic methodology is more efficient than those previously reported in the literature and also shows higher versatility towards the introduction of different side-chains at both C-7 and C-2. The obtained compound (±)- shows phytotoxicity against the grass-weed buffelgrass comparable to that of the natural phytotoxin radicinin (). Therefore, (±)- can constitute a more practical synthetic alternative to as bioherbicide for buffelgrass control.
本文报道了一种新型的（±）-3-去氧野百合碱（）的合成策略。该合成方法比文献中报道的方法更有效，并且在 C-7 和 C-2 位引入不同侧链的通用性也更高。所得化合物（±）-对杂草宽叶雀稗具有与天然植物毒素野百合碱（）相当的植物毒性。因此，（±）-可以作为生物除草剂替代野百合碱来控制宽叶雀稗。
