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中年女性 2 型糖尿病与肌肉骨骼症状。

Type 2 Diabetes and Musculoskeletal Symptoms Among Midlife Women.

机构信息

School of Nursing, Duke University, Durham, North Carolina.

出版信息

Diabetes Educ. 2019 Oct;45(5):520-528. doi: 10.1177/0145721719872558. Epub 2019 Sep 5.

Abstract

PURPOSE

The purpose of this study was to describe the association between type 2 diabetes and musculoskeletal symptoms among midlife women from 4 major racial/ethnic groups in the United States.

METHODS

This is a secondary data analysis using the data from 164 participants aged 40 to 60 years of 2 larger survey studies (62 with type 2 diabetes and 102 without type 2 diabetes). In the original studies, the participants completed multiple questionnaires on background characteristics, health status, menopausal status, and musculoskeletal symptoms. The Musculoskeletal Symptom Index for Midlife Women was used to determine the number and severity of musculoskeletal symptoms. For data analysis, independent tests, Mann-Whitney tests, and multiple regression analyses were used.

RESULTS

The mean number of musculoskeletal symptoms was significantly higher in women with vs without type 2 diabetes as was the mean severity score. In subgroup analyses, among each menopausal stage and non-Hispanic white women, there were significant differences in the numbers and total severity scores between those with type 2 diabetes and without type 2 diabetes. When background characteristics, health status, and menopausal status were controlled, having diagnosis of type 2 diabetes was positively associated with the numbers and total severity scores of musculoskeletal symptoms.

CONCLUSION

Study findings supported significant associations of type 2 diabetes with musculoskeletal symptoms among midlife women. Further studies are recommended to confirm relationships in larger populations.

摘要

目的

本研究旨在描述美国 4 大主要种族/族裔群体中年女性 2 型糖尿病与肌肉骨骼症状之间的关联。

方法

这是对 2 项更大规模调查研究(62 例患有 2 型糖尿病,102 例无 2 型糖尿病)中 164 名年龄在 40 至 60 岁的参与者数据的二次数据分析。在原始研究中,参与者完成了多项关于背景特征、健康状况、绝经状况和肌肉骨骼症状的问卷。使用中年女性肌肉骨骼症状指数来确定肌肉骨骼症状的数量和严重程度。数据分析采用独立样本 t 检验、Mann-Whitney U 检验和多元回归分析。

结果

患有 2 型糖尿病的女性肌肉骨骼症状的平均数量和严重程度评分均显著高于无 2 型糖尿病的女性。在亚组分析中,在每个绝经阶段和非西班牙裔白人女性中,患有 2 型糖尿病和无 2 型糖尿病的女性之间的症状数量和总严重程度评分存在显著差异。当控制背景特征、健康状况和绝经状况后,诊断为 2 型糖尿病与肌肉骨骼症状的数量和总严重程度评分呈正相关。

结论

研究结果支持中年女性 2 型糖尿病与肌肉骨骼症状之间存在显著关联。建议进一步研究以在更大的人群中确认这些关系。

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本文引用的文献

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Menopause and diabetes: EMAS clinical guide.绝经与糖尿病:欧洲绝经学会临床指南。
Maturitas. 2018 Nov;117:6-10. doi: 10.1016/j.maturitas.2018.08.009. Epub 2018 Aug 23.
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Musculoskeletal manifestations of diabetes mellitus.糖尿病的肌肉骨骼表现。
QJM. 2015 Nov;108(11):853-7. doi: 10.1093/qjmed/hcv106. Epub 2015 May 28.

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