Wilbur Joellen, Shaver Joan, Kogan Joseph, Buntin Mary, Wang Edward
College of Nursing, University of Illinois at Chicago, 60612, USA. jwilbur@uic..edu
Health Care Women Int. 2006 Aug;27(7):600-14. doi: 10.1080/07399330600803741.
We aimed to determine how menopausal transition symptoms cluster across 216 midlife women with fibromyalgia, chronic fatigue syndromes (FMS/CFS), or both and subsequently to compare symptom factor severity scores by menopausal status among these women and compare symptom reporting with prior community-based samples of women without obvious illness. We designed a cross-sectional telephone survey of 216 women aged 35 to 55, diagnosed with FMS/CFS, symptomatic in the prior 6 months, and without hysterectomy. Thirty-six of 61 symptoms loaded on five factors: aroused/anxious mood, depressed mood/withdrawal, musculoskeletal, gastrointestinal (GI), and vasomotor. Peri- and postmenopausal women had higher symptom severity scores for musculoskeletal, GI, and vasomotor factors but not mood factors. Symptoms for the women we studied who had FMS/CFS clustered similar to those in previous community-based samples of midlife women without major illness; however, the number of women experiencing symptoms was much higher among our sample.
我们旨在确定216名患有纤维肌痛、慢性疲劳综合征（纤维肌痛/慢性疲劳综合征）或两者皆有的中年女性的绝经过渡症状是如何聚集的，随后比较这些女性中不同绝经状态下的症状因子严重程度得分，并将症状报告与之前无明显疾病的社区女性样本进行比较。我们设计了一项横断面电话调查，对象为216名年龄在35至55岁之间、被诊断为纤维肌痛/慢性疲劳综合征、在过去6个月有症状且未接受子宫切除术的女性。61种症状中的36种症状归为五个因子：情绪激动/焦虑、情绪低落/退缩、肌肉骨骼、胃肠道和血管舒缩。围绝经期和绝经后女性在肌肉骨骼、胃肠道和血管舒缩因子方面的症状严重程度得分较高，但在情绪因子方面并非如此。我们研究的患有纤维肌痛/慢性疲劳综合征的女性的症状聚集情况与之前无重大疾病的社区中年女性样本相似；然而，我们样本中出现症状的女性数量要高得多。
