Murray Sarah J, Codina Charlotte J
Child Eye Care Associates, Tigard, Oregon.
Academic Unit of Ophthalmology and Orthoptics, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK.
J Binocul Vis Ocul Motil. 2019 Oct-Dec;69(4):141-152. doi: 10.1080/2576117X.2019.1656034. Epub 2019 Sep 5.
Anisometropic amblyopia is unilateral by definition and current treatment recommendations reflect that characteristic. However, recent research suggests a binocular component that deserves consideration. The aim of this review is to consider the levels of anisometropia deemed amblyogenic, and the cortical changes that occur in the presence of anisometropic amblyopia. Particular attention is given to cortical changes that impact the binocularity of these individuals. Knowledge of binocular deficits in anisometropic amblyopia has implications for current, accepted treatment regimens which are monocular in nature. Therefore, the integrity of binocular function in anisometropic amblyopia and its impact on the visual outcome will be evaluated. Given the rise in binocular treatments under clinical trial for amblyopia, this review also aims to evaluate the evidence of potentially enhanced benefits to anisometropic amblyopes from proposed new binocular therapies.
屈光参差性弱视根据定义是单侧性的，目前的治疗建议也反映了这一特征。然而，最近的研究表明存在一个值得考虑的双眼因素。本综述的目的是探讨被认为可导致弱视的屈光参差程度，以及屈光参差性弱视患者所发生的皮质变化。尤其要关注影响这些个体双眼视功能的皮质变化。了解屈光参差性弱视中的双眼缺陷对目前被广泛接受的单眼治疗方案具有重要意义。因此，将评估屈光参差性弱视中双眼视功能的完整性及其对视觉预后的影响。鉴于针对弱视的双眼治疗在临床试验中的应用不断增加，本综述还旨在评估新提出的双眼治疗方法对屈光参差性弱视患者可能带来更大益处的证据。
