Department of Ophthalmology, Saint Louis University School of Medicine, 1755 South Grand Blvd, Saint Louis, MO, 63104, USA.
Curr Rheumatol Rep. 2019 Sep 5;21(10):54. doi: 10.1007/s11926-019-0853-6.
The orbit is subject to a variety of vascular insults that manifest with both specific and nonspecific patterns of vision compromise. The aim of the following review is to highlight the ophthalmic clinical features of systemic vasculitides that most frequently involve the orbit and differentiate them from the most common non-vasculitic orbital disorders.
New studies continue to explore the autoimmune nature of vasculitic disease and seek to determine optimal use of newer therapies such as biologic agents. The pattern of ocular involvement in the context of clinical history allows the knowledgeable physician to distill a differential diagnosis into a specific or likely cause. Establishing a diagnosis in a timely fashion allows for a custom-tailored approach to therapy.
眼眶易受到多种血管损伤的影响,这些损伤表现出特定和非特定的视力损害模式。以下综述的目的是强调最常累及眼眶的系统性血管炎的眼部临床特征,并将其与最常见的非血管炎性眶内疾病区分开来。
新的研究继续探索血管炎疾病的自身免疫性质,并试图确定新型治疗方法(如生物制剂)的最佳使用方法。在临床病史的背景下,眼部受累的模式使有知识的医生能够将鉴别诊断归结为特定或可能的原因。及时做出诊断可以为治疗提供个性化的方法。