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睑板腺刮除术对沙眼性倒睫手术效果的潜在影响。

Potential Effect of Epilation on the Outcome of Surgery for Trachomatous Trichiasis.

作者信息

Talero Sandra Liliana, Muñoz Beatriz, West Sheila K

机构信息

Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD, USA.

出版信息

Transl Vis Sci Technol. 2019 Aug 21;8(4):30. doi: 10.1167/tvst.8.4.30. eCollection 2019 Jul.

Abstract

PURPOSE

To evaluate the association of epilation before surgery on the surgical outcome in trachomatous trichiasis (TT) patients.

METHODS

As a secondary data analysis, 1452 patients enrolled in the STAR trial were categorized according to preoperative epilation status. The main outcome was recurrent trichiasis after surgery. We used multivariable analysis, time-to-event analysis, and Cox proportional hazards model.

RESULTS

Those who epilated prior to surgery tended to be older and female, with worse entropion at baseline. The proportion with postoperative trichiasis was 7.7%, 8.8% in those who epilated versus 5.3% in those who did not ( = 0.03). Adjusting for age and sex, the risk of postoperative TT with epilation was 1.71 ( value = 0.02). Although entropion may be in the biological pathway from epilation to postoperative TT, we adjusted for entropion, and the risk of postoperative TT with epilation was 1.41 ( = 0.14).

CONCLUSIONS

The study suggests that preoperative epilation may increase the risk of postoperative trichiasis. Further research is needed to confirm the finding.

TRANSLATIONAL RELEVANCE

Patients with TT often self-treat, epilating their inturned eyelashes. The World Health Organization recommends surgery to treat TT, but when patients refuse the procedure or mild trichiasis is present, epilation is often recommended. There is some evidence that repetitive or improper epilation can be harmful to the lid and hair follicles. If there is damage to the lid margin, any subsequent surgery could have deleterious outcomes.

摘要

目的

评估沙眼性倒睫(TT)患者术前拔毛与手术效果之间的关联。

方法

作为二次数据分析,将参与STAR试验的1452例患者根据术前拔毛状态进行分类。主要结局是术后倒睫复发。我们采用多变量分析、事件发生时间分析和Cox比例风险模型。

结果

术前拔毛的患者往往年龄较大且为女性,基线时睑内翻情况更严重。术后倒睫的比例在拔毛患者中为7.7%、8.8%,而未拔毛患者中为5.3%(P = 0.03)。校正年龄和性别后,拔毛术后发生TT的风险为1.71(P值 = 0.02)。尽管睑内翻可能处于从拔毛到术后TT的生物学途径中,但我们校正了睑内翻因素后,拔毛术后发生TT的风险为1.41(P = 0.14)。

结论

该研究表明术前拔毛可能会增加术后倒睫的风险。需要进一步研究来证实这一发现。

转化相关性

TT患者常自行治疗,拔除内翻的睫毛。世界卫生组织建议手术治疗TT,但当患者拒绝手术或存在轻度倒睫时,通常推荐拔毛。有证据表明反复或不当拔毛可能对眼睑和毛囊有害。如果睑缘受损,任何后续手术都可能产生有害后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73d1/6707224/6a12b83c05cc/i2164-2591-8-4-30-f01.jpg

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