Department of Advanced Biomedical Sciences, University Federico II of Naples, Via S Pansini, I-80131, Naples, Italy.
J Cardiovasc Transl Res. 2020 Apr;13(2):238-244. doi: 10.1007/s12265-019-09911-3. Epub 2019 Sep 5.
We aim to validate echocardiographic left ventricular (LV) mass (echoLVM) in sixty-one patients with hypertrophic cardiomyopathy (HCM), using cardiac magnetic resonance measures (cmrLVM) as gold standard. cmrLVM was calculated using LV short-axis images, from base to apex, whereas echoLVM by LV epicardial minus LV endocardial volumes in 4 and 2 chamber views, using Simpson disk summation; trabeculae and papillary muscle were excluded in both cmrLVM and echoLVM. cmrLVM and echoLVM were not different by paired t test (145 ± 66 vs 147 ± 61; p = 0.240), and their correlation was good (r = 0.977; p < 0.0001). Intraclass correlation demonstrated reliability of echoLVM with cmrLVM (ρ = 0.987; Cls = 0.978-0.992; p < 0.0001). LV end-diastolic volume was higher by CMR than that by echo (137 ± 33 vs 85 ± 28 mL, p < 0.0001), resulting in a lower mass/volume ratio (1.1 ± 0.4 vs 1.8 ± 0.8, p < 0.0001). EchoLVM may be determined in patients with HCM. However, mass/volume ratio is higher by echocardiography than that by CMR.
我们旨在通过心脏磁共振（CMR）测量值（cmrLVM）作为金标准，验证 61 例肥厚型心肌病（HCM）患者的超声心动图左心室（LV）质量（echoLVM）。cmrLVM 通过 LV 短轴图像从基底到心尖计算，而 echoLVM 通过 LV 心外膜减去 4 腔和 2 腔视图中的 LV 心内膜体积，使用 Simpson 盘求和法；cmrLVM 和 echoLVM 均排除小梁和乳头肌。配对 t 检验显示 cmrLVM 和 echoLVM 无差异（145 ± 66 与 147 ± 61；p = 0.240），相关性良好（r = 0.977；p < 0.0001）。组内相关系数显示 echoLVM 与 cmrLVM 的可靠性（ρ = 0.987；Cls = 0.978-0.992；p < 0.0001）。CMR 测量的 LV 舒张末期容积高于超声心动图（137 ± 33 与 85 ± 28 mL，p < 0.0001），导致质量/容积比降低（1.1 ± 0.4 与 1.8 ± 0.8，p < 0.0001）。EchoLVM 可用于 HCM 患者。然而，超声心动图的质量/容积比高于 CMR。
