Hospital Universitário Professor Edgard Santos, Laboratório de Pesquisa em Doenças Infecciosas, Salvador, BA, Brazil.
Hospital Universitário Professor Edgard Santos, Laboratório de Pesquisa em Doenças Infecciosas, Salvador, BA, Brazil.
Braz J Infect Dis. 2019 Sep-Oct;23(5):313-321. doi: 10.1016/j.bjid.2019.08.001. Epub 2019 Sep 3.
The 36-Item Short Form Health Survey questionnaire (SF-36) is a widely used instrument for evaluating health-related quality-of-life (HRQoL). The psychometric validation of the SF-36 version 2.0 (SF-36v2) in HIV-infected patients had not yet conducted in Brazil.
To test data quality, reliability and validity of the SF-36v2 as a measure of HRQoL among Brazilian individuals living with HIV.
A cross-sectional study included 393 HIV-infected patients in whom HRQoL was assessed by using the SF-36v2 questionnaire. Demographic characteristics, socioeconomic status and clinical data were also collected. The SF-36 version 1 translated into Brazilian-Portuguese was adapted and introduced version 2 improvements according to the instrument developers. SPSS version 21 was used for data analyses. Confirmatory factor analysis (CFA) and structural equation modelling were performed using AMOS SPSS version 18. T-test for independent samples was used to compare differences between mean levels of HRQoL components in different groups. Linear multiple regression techniques were used to analyze the relationship between Physical Component Summary (PCS), Mental Component Summary (MCS) and independent variables.
We performed the CFA and tested the hypothetical measurement model. We included five parameters to improve the adherence of data to the model. All indicators met the requirement suggested by specialized literature (χ2 (gl): 980.7 (527); CFI: 0.949; GFI: 0.873; TLI: 0.943; RMSEA: 0.047; 90% IC: 0.042-0.051). Multiple regression analyses revealed that depression (p=0.001), family income (p=0.007), sex (p=0.001) and age (p<0.021) were associated with MCS. Comorbidities (p=0.001), health self-perception (p=0.001), age (p=0.001), and sex (p=0.025) were associated with PCS.
A consistent validation of the SF-36v2 in Brazilian HIV patients were shown. Further studies with SF-36v2 psychometric analyses would be required in other populations to establish Brazilian normative data.
36 项简明健康调查问卷（SF-36）是一种广泛用于评估健康相关生活质量（HRQoL）的工具。SF-36 版本 2.0（SF-36v2）在巴西的 HIV 感染者中的心理测量验证尚未进行。
测试 SF-36v2 在巴西 HIV 感染者中作为 HRQoL 测量工具的数据质量、信度和效度。
一项横断面研究纳入了 393 名 HIV 感染者，使用 SF-36v2 问卷评估 HRQoL。还收集了人口统计学特征、社会经济状况和临床数据。SF-36 版本 1 翻译成巴西葡萄牙语，根据仪器开发人员的要求进行了适应性调整和引入了版本 2 的改进。使用 SPSS 版本 21 进行数据分析。使用 AMOS SPSS 版本 18 进行验证性因子分析（CFA）和结构方程模型。使用独立样本 t 检验比较不同组间 HRQoL 成分的平均水平差异。使用线性多元回归技术分析生理成分综合评分（PCS）和心理成分综合评分（MCS）与自变量之间的关系。
我们进行了 CFA，并测试了假设的测量模型。我们纳入了五个参数来提高数据对模型的依从性。所有指标均符合专业文献建议的要求（χ2（gl）：980.7（527）；CFI：0.949；GFI：0.873；TLI：0.943；RMSEA：0.047；90%IC：0.042-0.051）。多元回归分析显示，抑郁（p=0.001）、家庭收入（p=0.007）、性别（p=0.001）和年龄（p<0.021）与 MCS 相关。合并症（p=0.001）、健康自我感知（p=0.001）、年龄（p=0.001）和性别（p=0.025）与 PCS 相关。
SF-36v2 在巴西 HIV 患者中得到了一致的验证。需要在其他人群中进行 SF-36v2 心理测量分析的进一步研究，以建立巴西的常模数据。
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