Fudan University School of Public Health, Shanghai, China.
School of Nursing, Fudan University, Shanghai, China.
Health Qual Life Outcomes. 2022 Jan 10;20(1):5. doi: 10.1186/s12955-021-01910-w.
To identify and assess the psychometric properties of patient-reported outcome measures (PROMs) of health-related quality of life (HRQoL) in people living with HIV (PLWH).
Nine databases were searched from January 1996 to October 2020. Methodological quality was assessed by using the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) Risk of Bias Checklist. We used the COSMIN criteria to summarize and rate the psychometric properties of each PROM. A modified Grading, Recommendations, Assessment, Development, and Evaluation (GRADE) system was used to assess the certainty of evidence.
Sixty-nine studies reported on the psychometric properties of 30 identified instruments. All studies were considered to have adequate methodological quality in terms of content validity, construct validity, and internal consistency. Limited information was retrieved on cross-cultural validity, criterion validity, reliability, hypothesis testing, and responsiveness. High-quality evidence on psychometric properties was provided for the Medical Outcomes Study HIV Health Survey (MOS-HIV), the brief version of the World Health Organization's Quality of Life Instrument in HIV Infection (WHOQoL-HIV-BREF), 36-Item Short Form Survey (SF-36), Multidimensional Quality of Life Questionnaire for Persons with HIV/AIDS (MQoL-HIV), and WHOQoL-HIV.
The findings from the included studies highlighted that among HIV-specific and generic HRQoL PROMs, MOS-HIV, WHOQoL-HIV-BREF, SF-36, MQoL-HIV, and WHOQoL-HIV are strongly recommended to evaluate HRQoL in PLWH in research and clinics based on the specific aims of assessments and the response burden for participants.
识别和评估与健康相关的生活质量（HRQoL）的患者报告结局测量（PROMs）在艾滋病毒感染者（PLWH）中的心理测量特性。
从 1996 年 1 月至 2020 年 10 月，检索了 9 个数据库。使用共识基础的健康测量仪器选择标准（COSMIN）偏倚风险检查表评估方法学质量。我们使用 COSMIN 标准来总结和评估每个 PROM 的心理测量特性。使用改良的 Grading, Recommendations, Assessment, Development, and Evaluation (GRADE) 系统来评估证据的确定性。
69 项研究报告了 30 种确定工具的心理测量特性。所有研究在内容有效性、结构有效性和内部一致性方面都被认为具有足够的方法学质量。关于跨文化有效性、效标效度、可靠性、假设检验和反应性，仅检索到有限的信息。提供了关于心理测量特性的高质量证据，包括医疗结局研究艾滋病毒健康调查（MOS-HIV）、世界卫生组织艾滋病毒感染生活质量工具的简短版本（WHOQoL-HIV-BREF）、36 项简短形式调查（SF-36）、艾滋病毒感染者多维生活质量问卷（MQoL-HIV）和 WHOQoL-HIV。
纳入研究的结果强调，在 HIV 特异性和一般性 HRQoL PROMs 中，MOS-HIV、WHOQoL-HIV-BREF、SF-36、MQoL-HIV 和 WHOQoL-HIV 强烈建议根据评估的具体目标和参与者的反应负担，在研究和临床中用于评估 PLWH 的 HRQoL。
