Department of Neuroscience and Pharmacology, BRAINlab, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Faculty of Psychology, Department of Basic Psychological Research and Research Methods, University of Vienna, Liebiggasse 5, A-1010 Vienna, Austria.
Brain Cogn. 2019 Nov;136:103597. doi: 10.1016/j.bandc.2019.103597. Epub 2019 Sep 3.
Parkinson's disease (PD) is a progressing neurodegenerative disease predominantly involving the loss of dopamine producing neurons with hallmark symptoms of motor disorders and cognitive, motivational, emotional, and perceptual impairments. Intriguingly, PD can also be connected-often anecdotally-with a sudden burst of artistic creativity, motivation, or changed quality/style of produced art. This has led to growing empirical interest, promising a window into brain function and the unique neurological signature of artists. This topic also fits a growing interest from researchers in other areas, including Alzheimer's or other dementia, which have suggested that specific changes in art production/appraisal may provide a unique basis for therapy, diagnosis, or understanding of these diseases. However, whether PD also shows similar impacts on how we perceive and evaluate art has never been systematically addressed. We compared a cohort of PD patients against age-matched healthy controls, asking participants to rate paintings using scales of liking and beauty and terms pertaining to artworks' formal and conceptual qualities previously designed to provide a rubric for symptom identification. We found no evidence for PD-related differences in liking or beauty. However, PD patients showed higher ratings on assessed "emotionality," potentially relating to the tie between PD, dopamine pathways, and emotion/reward.
帕金森病（PD）是一种进行性神经退行性疾病，主要涉及产生多巴胺的神经元丧失，其标志性症状为运动障碍以及认知、动机、情感和感知障碍。有趣的是，PD 还可以与艺术创作的突然爆发有关——通常是轶事——这种爆发涉及艺术创作的动机、动力或产生的艺术的质量/风格的改变。这引起了越来越多的实证研究兴趣，为探索大脑功能和艺术家独特的神经特征提供了一个窗口。这个话题也符合其他领域研究人员日益增长的兴趣，包括阿尔茨海默病或其他痴呆症，这些研究表明，艺术创作/评估的特定变化可能为这些疾病的治疗、诊断或理解提供独特的基础。然而，PD 是否也会对我们感知和评价艺术的方式产生类似的影响，这一点从未得到系统的研究。我们比较了一组 PD 患者和年龄匹配的健康对照组，要求参与者使用喜欢和美丽的量表以及与艺术品的形式和概念质量有关的术语来对画作进行评分，这些术语之前被设计用来为症状识别提供一个准则。我们没有发现 PD 相关的喜好或美感差异的证据。然而，PD 患者在评估的“情感”方面得分更高，这可能与 PD、多巴胺途径和情感/奖励之间的联系有关。
