Institute of Psychology, Leiden University, AK Leiden 2333, the Netherlands; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health, Amsterdam 1081 HV, the Netherlands.
Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health, Amsterdam 1081 HV, the Netherlands.
J Affect Disord. 2020 Jan 1;260:77-83. doi: 10.1016/j.jad.2019.08.090. Epub 2019 Aug 29.
Signs and symptoms of psychopathology can be chronic but are generally regarded as less stable over time than markers of cognitive vulnerability and personality. Some findings suggest that these differences in temporal stability are modest in size but a rigorous examination across concepts is lacking. The current study investigated the temporal stability of affective symptoms, cognitive vulnerability markers and personality traits at various assessments over nine years.
Participants of the Netherlands Study of Depression and Anxiety were assessed at baseline and reassessed after 2, 4, 6 and 9 years. They were grouped on the basis of waves of depression and anxiety CIDI-diagnoses into stable healthy (n = 768), stable patients (n = 352) and unstable patients (n = 821). We determined temporal stability by calculating intraclass correlation coefficients (ICC) and consistency indices of latent state-trait analyses (LST).
Temporal stability was moderate to high for symptoms (range ICC's 0.54-0.73; range consistency 0.64-0.74), cognitive vulnerability (range ICC's 0.53-0.76; range consistency 0.60-0.74) and personality (range ICC's 0.57-0.80; range consistency.60 -0.75). Consistency indices for all measures were on average a bit lower in the unstable group (ICC = 0.54) compared to the stable groups (ICC = 0.61). Overall stability was similarly high after 2, 4, 6 and 9 years.
The 9-year stability over time of symptoms of affective disorders and that of indices of cognitive vulnerability and personality are remarkably similar and relatively high.
精神病理学的症状和体征可能是慢性的，但通常被认为不如认知脆弱性和人格的标志物稳定。一些研究结果表明，这些时间稳定性差异的规模适中，但缺乏对各种概念的严格检验。本研究调查了情感症状、认知脆弱性标志物和人格特质在九年的多次评估中的时间稳定性。
荷兰抑郁和焦虑研究的参与者在基线时进行评估，并在 2、4、6 和 9 年后重新评估。他们根据抑郁和焦虑 CIDI 诊断的波次分为稳定健康组（n=768）、稳定患者组（n=352）和不稳定患者组（n=821）。我们通过计算内在一致性系数（ICC）和潜在状态-特质分析的一致性指数（LST）来确定时间稳定性。
症状（ICC 范围为 0.54-0.73；一致性范围为 0.64-0.74）、认知脆弱性（ICC 范围为 0.53-0.76；一致性范围为 0.60-0.74）和人格（ICC 范围为 0.57-0.80；一致性范围为 0.60-0.75）的时间稳定性为中等至高。与稳定组（ICC=0.61）相比，不稳定组的所有测量指标的一致性指数平均略低（ICC=0.54）。在 2、4、6 和 9 年后，整体稳定性也非常高。
情感障碍症状、认知脆弱性指数和人格的 9 年时间稳定性相似且相对较高。
