Department of Physics, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Biophys J. 2019 Sep 17;117(6):1051-1056. doi: 10.1016/j.bpj.2019.08.016. Epub 2019 Aug 22.
Extraction from simulations of the area compressibility moduli of the monolayers in a bilayer is considered theoretically. A statistical mechanical derivation shows that the bilayer modulus is the sum of the two monolayer moduli, as is often supposed but contrary to a recent study. Seemingly plausible assumptions regarding fluctuations are tested rigorously. Prospects for future research are discussed.
从双层膜中单分子层的面积压缩模量的模拟中提取出来的内容在理论上进行了考虑。统计力学的推导表明，双层膜的模量是两个单分子层模量的和，这与通常的假设一致，但与最近的一项研究相反。对关于涨落的看似合理的假设进行了严格的检验。讨论了未来研究的前景。
