Yamagata J, Barnett E V, Knutson D W, Nasu H, Chia D
J Immunol Methods. 1979;29(1):43-56. doi: 10.1016/0022-1759(79)90124-8.
A sensitive direct binding radioimmunoassay (RIA) was developed which detected low avidity anti-IgG antibodies in sera negative in the latex fixation test (LFT). IgG class antibodies could be detected and were commonly found along with IgM class antibodies. Additionally, the RIA was more reproducible than the LFT, was easily adapted to measure relative avidities of anti-IgG antibodies, and had other technical advantages over the LFT.
开发了一种灵敏的直接结合放射免疫测定法（RIA），该方法可检测乳胶凝集试验（LFT）阴性血清中的低亲和力抗IgG抗体。可以检测到IgG类抗体，并且通常与IgM类抗体一起发现。此外，RIA比LFT具有更高的重复性，易于用于测量抗IgG抗体的相对亲和力，并且在技术上比LFT具有其他优势。
