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后路颈椎椎板切除术治疗多节段退变性颈椎脊髓病的长期疗效

The Efficacy of Posterior Cervical Laminectomy for Multilevel Degenerative Cervical Spondylotic Myelopathy in Long Term Period.

作者信息

Kire Neilakuo, Jain Sanyam, Merchant Zahir Abbas, Kundnani Vishal

机构信息

Spine Unit, Department of Orthopeadics, Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.

出版信息

Asian J Neurosurg. 2019 Jul-Sep;14(3):848-852. doi: 10.4103/ajns.AJNS_49_19.

Abstract

STUDY DESIGN

This was a retrospective analysis.

BACKGROUND

Surgical decompression is the gold standard for preventing the progression of neurological deficit in degenerative multilevel cervical spondylotic myelopathy (CSM). The efficacy of posterior laminectomy in the surgical management of CSM has been described in the past, but long-term follow-up data are scanty.

OBJECTIVE

The aim of this study is to assess the long-term clinical-radiological outcomes following posterior cervical decompressive laminectomy in multilevel degenerative CSM.

MATERIALS AND METHODS

A retrospective analysis of 110 patients with degenerative multilevel CSM who underwent posterior cervical laminectomy alone in a single hospital by a single surgeon from 2009 to 2013 with minimum 5-year follow-up. Pre- and post-operative clinical parameters (visual analog scale [VAS], Nurick and modified Japanese orthopedic association [mJOA]), radiological parameter (Sagittal cervical Cobb's Angle), perioperative complications (time, blood loss, and hospital stay), postoperative complications (infection, C5 palsy, and neurological worsening) were evaluated.

RESULTS

Totally 110 patients (males - 68 and females - 42) with age varying from 46 to 80 (mean-57) years, and the mean duration of illness was 3 months were evaluated. Mean clinical parameters are VAS (preoperative = 5 ± 1.31, postoperative = 1.49 ± 0.687), Nurick grading (preoperative = 3.23 ± 71, postoperative = 1.924 ± 0.75), and mJOA (preoperative = 6.32 ± 0.87, postoperative = 9.89 ± 1.37). The mean blood loss was 93.95 ± 19.18 ml, and the mean time taken for surgery was 83.65 ± 10.18 min. About 13% ( = 15) patients developed cervical kyphosis and 29% ( = 32) developed changes in cervical spine alignment and 10% ( = 11) developed worsening of neurology at final follow-up. Two patients developed a superficial infection which was managed with antibiotics. Three patients developed C5 palsy which recovered with due time.

CONCLUSIONS

With the proper selection of patients, posterior cervical laminectomy is effective in offering a clinical improvement to patients with degenerative multilevel CSM with a low incidence of clinically significant radiological deterioration.

摘要

研究设计

本研究为回顾性分析。

背景

手术减压是预防退行性多节段颈椎病性脊髓病(CSM)神经功能缺损进展的金标准。过去已有关于后路椎板切除术治疗CSM疗效的描述,但长期随访数据较少。

目的

本研究旨在评估多节段退行性CSM患者行后路颈椎减压椎板切除术后的长期临床和影像学结果。

材料与方法

对2009年至2013年期间在一家医院由一名外科医生单独进行后路颈椎椎板切除术的110例多节段退行性CSM患者进行回顾性分析,随访时间至少5年。评估术前和术后的临床参数(视觉模拟评分法[VAS]、努里克评分和改良日本骨科协会[mJOA]评分)、影像学参数(颈椎矢状面Cobb角)、围手术期并发症(时间、失血量和住院时间)、术后并发症(感染、C5麻痹和神经功能恶化)。

结果

共评估了110例患者(男性68例,女性42例),年龄在46至80岁之间(平均57岁),平均病程3个月。平均临床参数为VAS(术前=5±1.31,术后=1.49±0.687)、努里克分级(术前=3.23±0.71,术后=1.924±0.75)和mJOA评分(术前=6.32±0.87,术后=9.89±1.37)。平均失血量为93.95±19.18ml,平均手术时间为83.65±10.18分钟。在末次随访时,约13%(n=15)的患者出现颈椎后凸,29%(n=32)的患者颈椎排列发生改变,10%(n=11)的患者神经功能恶化。2例患者发生浅表感染,经抗生素治疗。3例患者发生C5麻痹,随时间推移恢复。

结论

通过适当选择患者,后路颈椎椎板切除术可有效改善多节段退行性CSM患者的临床症状,且具有临床意义的影像学恶化发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4daa/6703065/cdfe282441e2/AJNS-14-848-g001.jpg

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