开拓新方向：肌球蛋白2、Piezo与新陈代谢。
Pulling in new directions: Myosin 2, Piezo, and metabolism.
作者信息
Quintanilla Melissa A, Hammer John A, Beach Jordan R
机构信息
Cell and Molecular Physiology, Loyola University Chicago, Stritch School of Medicine, Center for Translational Research and Education, Maywood, IL, USA.
Cell and Developmental Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
出版信息
F1000Res. 2019 Aug 22;8. doi: 10.12688/f1000research.18856.1. eCollection 2019.
Abstract
Myosin 2 plays a central role in numerous, fundamental, actin-based biological processes, including cell migration, cell division, and the adhesion of cells to substrates and other cells. Here, we highlight recent studies in which the forces created by actomyosin 2 have been shown to also impact tension-sensitive ion channels and cell metabolism.
摘要
肌球蛋白2在众多基于肌动蛋白的基本生物学过程中发挥着核心作用，包括细胞迁移、细胞分裂以及细胞与底物和其他细胞的黏附。在此，我们重点介绍了最近的一些研究，这些研究表明，肌动球蛋白2产生的力也会影响张力敏感离子通道和细胞代谢。
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