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腮腺多形性腺瘤切除术后的并发症:对2002年至2016年297例患者的长期随访及文献综述

Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications.

作者信息

Bonavolontà Paola, Dell'Aversana Orabona Giovanni, Maglitto Fabio, Abbate Vincenzo, Committeri Umberto, Salzano Giovanni, Improta Giovanni, Iaconetta Giorgio, Califano Luigi

机构信息

Department Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.

Department Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.

出版信息

Br J Oral Maxillofac Surg. 2019 Dec;57(10):998-1002. doi: 10.1016/j.bjoms.2019.08.008. Epub 2019 Sep 6.

Abstract

Pleomorphic adenomas are rounded, lumpy, capsulated lesions that are more common in women. They are typically benign, but can be associated with malignancy in a minority of cases (such as carcinoma ex pleomorphic adenoma), between 3% - 12% of the time, according to available data. The purpose of our study was to evaluate clinical outcomes in patients with benign parotid gland tumours after extracapsular dissection (ECD) or superficial parotidectomy (SP). We made a retrospective study of 297 patients who had had benign tumours of the parotid gland, and had been referred to our department from 2002 - 2016 to have either procedure. We measured the statistical differences between the two techniques (evaluated recurrence rate and complications) with the chi squared test. The chosen level of statistical significance was p<0.05. Median (range) follow-up time was 43 months (25-168) months. Haematoma and hypoaesthesia were significantly more common after SP than after ECD (8.9% compared with 7.7%, and 16.8% compared with 5.6%, respectively). Transient facial nerve injury, Frey syndrome, and facial paralysis were significantly more common after SP than after ECD (23.6% compared with 1.5%, 6.7% compared with 1% and 6,7% compared with 0%, respectively). ECD had the advantage of reduced operating time, lower morbidity and lower recurrence rate, and could be considered the treatment of choice for pleomorphic adenoma of the parotid gland up (to 3cm) which are mobile and sited in the superficial lobe of the parotid gland.

摘要

多形性腺瘤是圆形、块状、有包膜的病变,在女性中更为常见。它们通常是良性的,但在少数情况下(如多形性腺瘤恶变)可能与恶性肿瘤相关,根据现有数据,这种情况在3% - 12%的时间里会出现。我们研究的目的是评估在进行囊外剥离术(ECD)或腮腺浅叶切除术(SP)后,腮腺良性肿瘤患者的临床结局。我们对297例患有腮腺良性肿瘤的患者进行了回顾性研究,这些患者在2002年至2016年期间被转诊至我们科室接受这两种手术中的一种。我们用卡方检验测量了两种技术之间的统计学差异(评估复发率和并发症)。选定的统计学显著性水平为p<0.05。中位(范围)随访时间为43个月(25 - 168个月)。SP术后血肿和感觉减退明显比ECD术后更常见(分别为8.9% 与7.7%,以及16.8%与5.6%)。SP术后短暂性面神经损伤、Frey综合征和面瘫明显比ECD术后更常见(分别为23.6%与1.5%,6.7%与1%,以及6.7%与0%)。ECD具有手术时间缩短、发病率较低和复发率较低的优势,对于位于腮腺浅叶、可移动且大小在(3cm)以下的腮腺多形性腺瘤,可被视为首选治疗方法。

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