Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Sorbonne Université , Paris , France.
Institut Natinal de la santé et de la Recherche Médicale (INSERM) , Paris , France.
Crit Rev Clin Lab Sci. 2019 Dec;56(8):526-532. doi: 10.1080/10408363.2019.1653820. Epub 2019 Sep 10.
Iron deficiency is the most common micronutrient deficiency in the world and represents a major challenge for public health, notably in terms of morbidity and mortality. It remains largely under-diagnosed due to the low level of exploration and the absence of international harmonization for biological tests and thresholds. We performed a systematic review of the literature using PubMed, which allowed us to identify 41 publications within the scope of this review. This analysis shows the benefit of using transferrin saturation in addition to ferritin, in the diagnosis of iron deficiency and even in first-line analysis for patients with chronic inflammatory diseases.
缺铁是世界上最常见的微量营养素缺乏症，对公共健康构成重大挑战，尤其是在发病率和死亡率方面。由于对生物检测和阈值的探索程度低且缺乏国际协调，缺铁的诊断仍然在很大程度上未得到充分诊断。我们使用 PubMed 对文献进行了系统回顾，这使我们能够在本综述范围内确定了 41 篇出版物。该分析表明，除了铁蛋白外，转铁蛋白饱和度在缺铁诊断中甚至在慢性炎症性疾病患者的一线分析中都具有优势。
