民族精神药理学的新研究进展：亚洲视角
New research advances in ethnopsychopharmacology: an Asian perspective.
作者信息
Pi Edmond H, Zhu Weiguo
机构信息
Department of Psychiatry and Behavioral Sciences, University of Southern California, Keck School of Medicine, 2020 Zonal Avenue, IRD, Los Angeles, CA 90033, USA, email
出版信息
Int Psychiatry. 2007 Jul 1;4(3):57-58. eCollection 2007 Jul.
Asians represent more than half the world's population but themselves consist of very diverse genetic, ethnic, cultural and linguistic groups. Understanding the role of ethnicity in an individual's response to psychotropic medications is of importance in treating psychiatric disorders among Asians. Recent research has supported the notion that Asians carry distinct genetic profiles that can influence both the pharmacokinetics and the pharmacodynamics of a given medication (Lin & Smith, 2000; Pi & Simpson, 2005). In this brief review, we summarise the research findings in the field, focusing on pharmacogenetic variations between Asians and other ethnic groups.
亚洲人占世界人口的一半以上，但其本身由非常多样化的基因、种族、文化和语言群体组成。了解种族因素在个体对精神药物反应中的作用，对于治疗亚洲人的精神疾病至关重要。最近的研究支持了这样一种观点，即亚洲人具有独特的基因特征，这些特征可以影响特定药物的药代动力学和药效学（Lin & Smith，2000；Pi & Simpson，2005）。在这篇简短的综述中，我们总结了该领域的研究结果，重点关注亚洲人与其他种族群体之间的药物遗传学差异。
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