Iwegbue Chukwujindu M A, Emakunu Omotekoro S, Lari Bulouebibo, Egobueze Francis E, Tesi Godswill O, Nwajei Godwin E, Martincigh Bice S
Department of Chemistry, Delta State University, P.M.B. 1, Abraka, Nigeria.
Department of Science Laboratory Technology, Delta State University, P.M.B. 1, Abraka, Nigeria.
Toxicol Rep. 2019 Aug 24;6:914-923. doi: 10.1016/j.toxrep.2019.08.014. eCollection 2019.
This study presents data on the levels and risk of human exposure to Cd, Pb, Cr, Ni, Cu, Co, Mn, Zn and Fe in some popular brands of household hygienic products (HHPs) available in Nigeria. The HHPs were digested with a mixture of HNO, HCl and HClO in a ratio of 1:3:1 and the concentrations of the selected metals were quantified by atomic absorption spectrophotometry. The metal concentrations (in μg g) in these products ranged from 0.4 to 5.4, <0.09-47.0, <0.12-43.7, <0.06-7.5, <0.12-9.5, <0.06-15.0, <0.09-24.5, 9.0-675 and 62.4-434 for Cd, Pb, Cr, Cu, Co, Ni, Mn, Zn and Fe respectively. The systemic exposure dosages for the metals, arising from the use of these HPPs, were less than their respective provisional tolerable daily intake/recommended dietary allowance values. The household hygienic products are safe to use by humans based on the margin of safety values that were all above 100. However, the products contained significant levels of toxic (Cd and Pb), allergenic (Ni and Cr) and other low toxicity metals (Mn, Zn and Fe), which could be a potential threat to the environment.
本研究展示了尼日利亚市场上一些常见品牌家用卫生用品（HHPs）中镉（Cd）、铅（Pb）、铬（Cr）、镍（Ni）、铜（Cu）、钴（Co）、锰（Mn）、锌（Zn）和铁（Fe）的含量水平及人体接触风险。将这些家用卫生用品用硝酸（HNO）、盐酸（HCl）和高氯酸（HClO）按1:3:1的比例混合进行消解，并用原子吸收分光光度法定量所选金属的浓度。这些产品中金属浓度（μg/g）分别为：镉0.4至5.4、铅<0.09至47.0、铬<0.12至43.7、铜<0.06至7.5、钴<0.12至9.5、镍<0.06至15.0、锰<0.09至24.5、锌9.0至675、铁62.4至434。因使用这些家用卫生用品而产生的金属全身暴露剂量低于其各自的暂定每日耐受摄入量/推荐膳食摄入量值。基于安全系数均高于100，这些家用卫生用品对人类使用是安全的。然而，这些产品含有大量有毒金属（镉和铅）、致敏金属（镍和铬）以及其他低毒性金属（锰、锌和铁），这可能对环境构成潜在威胁。
