某些麦角生物碱对大脑还原型谷胱甘肽的影响。
Influence of some ergot alkaloids on the cerebral reduced glutathione.
作者信息
Gorini A, Arnaboldi R, Vercesi L, Dossena M
机构信息
Istituto di Farmacologia, Università di Pavia, Italy.
出版信息
Farmaco Sci. 1988 Nov;43(11):887-90.
PMID:3150835
Abstract
Dose-related changes of the reduced glutathione were evaluated in forebrains from male Wistar rats aged 10 months after chronic i.p. treatment for two months with the ergot alkaloids dihydroergocristine and dihydroergocriptine. The results indicate that, within a specific dose-range, the concentration of the cerebral reduced glutathione may be modified by exogenous intervention.
摘要
对10月龄雄性Wistar大鼠进行为期两个月的腹腔注射麦角生物碱二氢麦角隐亭和二氢麦角克碱慢性处理后，评估其前脑内还原型谷胱甘肽的剂量相关变化。结果表明，在特定剂量范围内，脑内还原型谷胱甘肽的浓度可通过外源干预进行调节。
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