Ryoo Seung-Bum, Oh Heung-Kwon, Ha Heon-Kyun, Han Eon Chul, Kwon Yoon-Hye, Song Inho, Moon Sang Hui, Choe Eun Kyung, Park Kyu Joo
Division of Colorectal Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Division of Colorectal Surgery, Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Ann Surg Treat Res. 2019 Sep;97(3):149-156. doi: 10.4174/astr.2019.97.3.149. Epub 2019 Aug 29.
Rectovaginal fistula can result from various causes and diverse surgical procedures have developed as a result. We investigated the outcomes of surgical treatments for rectovaginal fistula according to causes and procedures.
Between 1998 and 2016, 92 patients underwent 128 operations for rectovaginal fistula. Prospectively collected data were recorded, and a retrospective review was conducted.
The median age was 49 years, and low fistula occurred in 58 patients (63.0%). The most common cause was radiation therapy, followed by pelvic operation, birth injury, perineal operation, cancer invasion, and trauma. The most common procedure during the first operation was diverting ostomy alone, followed by transanal rectal advancement flap, sphincteroplasty with perineoplasty, bowel resection, fistulectomy with seton placement, and Martius flap. Thirty-one patients (33.7%) experienced successful closure after the first operation. Repeated operations were performed in 16 patients (17.4%), including gracilis muscle transpositions, stem cell injections, and Martius flaps. The overall success rate was 42.4% (n = 39). Radiation therapy and pelvic operation as cause of fistula were significantly poor prognostic factors (P = 0.010, P = 0.045) and Crohn disease had a tendency for poor prognostic factors (P = 0.058).
Radiation therapy and pelvic operation for cancer were more common causes than birth injury, and these causes of rectovaginal fistula were the most important prognostic factors. An individualized approach and repeated surgeries with complex or newly developed procedures, even among high-risk causes of fistula, may be necessary to achieve successful closure.
直肠阴道瘘可由多种原因引起,相应地也发展出了多种外科手术方法。我们根据病因和手术方法对直肠阴道瘘的外科治疗结果进行了研究。
1998年至2016年间,92例患者接受了128次直肠阴道瘘手术。记录前瞻性收集的数据,并进行回顾性分析。
患者中位年龄为49岁,58例(63.0%)为低位瘘。最常见的病因是放射治疗,其次是盆腔手术、产伤、会阴手术、癌症侵犯和创伤。首次手术最常用的方法是单纯转流造口术,其次是经肛门直肠推进皮瓣术、括约肌成形术与会阴成形术、肠切除术、带挂线的瘘管切除术和Martius皮瓣术。31例患者(33.7%)首次手术后成功闭合。16例患者(17.4%)接受了再次手术,包括股薄肌移位术、干细胞注射和Martius皮瓣术。总体成功率为42.4%(n = 39)。放射治疗和盆腔手术作为瘘管病因是显著的不良预后因素(P = 0.010,P = 0.045),克罗恩病有不良预后因素的倾向(P = 0.058)。
癌症的放射治疗和盆腔手术是比产伤更常见的病因,这些直肠阴道瘘的病因是最重要的预后因素。即使在瘘管的高危病因中,可能也需要采用个体化方法并进行复杂或新开发手术的重复手术,以实现成功闭合。