Eftekhar Maryam, Saeed Lida, Hoseini Masrooreh
Yazd Reasearch and Clinical Center for Infertility, Yazd Reproductive Science Institute, Shahid Sadoughi University, Yazd, Iran.
Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran.
Int J Reprod Biomed. 2019 Jul 31;17(7):481-486. doi: 10.18502/ijrm.v17i7.4859. eCollection 2019 Jul.
Embryo transfer (ET) is the last and the most clinical process in assisted reproductive technology cycle. It has been suggested that cervical mucus interacts with an adequate embryo transfer in different ways. A few studies showed that catheter rotation could discharge mucus entrapped in the embryo to neutralize embryo displacement.
The aim of this present study was to compare the outcome of frozen embryo transfer (FET) based on catheter rotation during withdrawal.
In this case-control study, the clinical documents of 240 women who experienced frozen embryo transfer cycles were reviewd. The subjects were divided into two groups (n = 120/each), including A) the rotation treatment group (360°) that underwent ET using catheter rotation and B) the control group including the subjects who experienced ET with no catheter rotation. Clinical and chemical pregnancies and implantation rates were compared between two groups.
Results showed that there is no significant difference between the basic clinical and demographic features of both groups (p 0.05). A significant difference was observed in terms of the rate of chemical pregnancy between groups (21.7% vs 43.3%, p = 0.001 respectively). In addition, the rate of clinical pregnancy was significantly higher in study group than the control (33.35% vs 14.2%, p = 0.002 respectively).
Our results demonstrated that catheter rotation during withdrawal increased the implantation rate and clinical pregnancy.
胚胎移植（ET）是辅助生殖技术周期中的最后也是最具临床意义的过程。有研究表明，宫颈黏液以不同方式影响胚胎移植的效果。一些研究显示，导管旋转可排出胚胎周围的黏液，以抵消胚胎移位。
本研究旨在比较胚胎移植过程中导管旋转对冻融胚胎移植（FET）结局的影响。
在这项病例对照研究中，回顾了240例行冻融胚胎移植周期的妇女的临床资料。将研究对象分为两组（每组n = 120），包括A）导管旋转治疗组（360°），采用导管旋转进行胚胎移植；B）对照组，即未进行导管旋转的胚胎移植患者。比较两组的临床妊娠率、生化妊娠率和着床率。
结果显示，两组的基本临床特征和人口统计学特征无显著差异（p > 0.05）。两组间生化妊娠率有显著差异（分别为21.7%和43.3%，p = 0.001）。此外，研究组的临床妊娠率显著高于对照组（分别为33.35%和14.2%，p = 0.002）。
我们的结果表明，胚胎移植过程中导管旋转可提高着床率和临床妊娠率。
