Centre for Gerontological Nursing, School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
Centre for Gerontological Nursing, School of Nursing, The Hong Kong Polytechnic University.
Phys Ther. 2019 Dec 16;99(12):1616-1627. doi: 10.1093/ptj/pzz130.
Although the evidence suggests that general fatigue is a strong indicator of rapid aging, frailty, and disability, general fatigue is undertreated in gerontological care.
The aim of this study is to investigate whether an individualized exercise program with and without behavioral change enhancement (BCE) strategies for older people who are frail and have general fatigue will reduce their fatigue and symptoms of frailty.
A 3-arm, single-blind, cluster randomized controlled trial registered with ClinicalTrials.gov (NCT03394495) will be conducted.
The study will be conducted in a community setting.
Two hundred eighty-five community-dwelling older people with general fatigue will be recruited from 12 district community health centers.
People from each center will be randomized to one of three groups. The combined group will receive a 16-week combined intervention consisting of individualized exercise training and the BCE program, plus two booster sessions at 2 and 6 months after the program. The exercise group will receive exercise training and health talks only. The control group will receive health talks only.
Outcome measures will be collected at baseline, at the midpoint (week 8) of the program, and then at 1 week, 6 months, and 12 months after the end of the program. The primary outcome---level of fatigue---will be measured using the Multidimensional Fatigue Inventory. Secondary outcomes will include the participants' frailty status, strength, mobility, exercise self-efficacy, and habitual physical activity.
A self-reported level of fatigue will be used.
The effect of exercise and BCE strategies on general fatigue among older people who are frail is not known. This study will be a pioneering interventional study on how general fatigue among older people who are frail can be managed and how fatigue-related frailty can be prevented or minimized.
尽管有证据表明全身疲劳是快速衰老、虚弱和残疾的强烈指标，但老年医学护理中对全身疲劳的治疗不足。
本研究旨在探讨针对虚弱和全身疲劳的老年人，是否一种包含行为改变增强（BCE）策略的个体化运动方案能减轻他们的疲劳和虚弱症状。
这是一项三臂、单盲、整群随机对照试验，已在 ClinicalTrials.gov 注册（NCT03394495）。
研究将在社区环境中进行。
将从 12 个区社区卫生中心招募 285 名有全身疲劳的社区居住老年人。
每个中心的人将随机分配到三组之一。综合组将接受为期 16 周的综合干预，包括个体化运动训练和 BCE 方案，以及方案结束后 2 个月和 6 个月的两次强化疗程。运动组仅接受运动训练和健康讲座。对照组仅接受健康讲座。
将在基线、方案中点（第 8 周）以及方案结束后 1 周、6 个月和 12 个月收集结局测量。主要结局指标——疲劳程度——将使用多维疲劳量表进行测量。次要结局指标将包括参与者的虚弱状态、力量、移动能力、运动自我效能感和习惯性体力活动。
将使用自我报告的疲劳程度。
尚不清楚运动和 BCE 策略对虚弱老年人全身疲劳的影响。这项研究将是一项开创性的干预研究，旨在探讨如何管理虚弱老年人的全身疲劳，以及如何预防或最小化与疲劳相关的虚弱。
