Department of Rehabilitation Medicine, University of Kansas Medical Center, Kansas City, KS, USA; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA.
Department of Biomedical Engineering, Washington University, St. Louis, MO, USA; Department of Neurological Surgery, Washington University, St. Louis, MO, USA; Center of Innovation in Neuroscience and Technology, Washington University, St. Louis, MO, USA.
Trends Neurosci. 2019 Nov;42(11):825-839. doi: 10.1016/j.tins.2019.08.008. Epub 2019 Sep 10.
Whereas voluntary movements have long been understood to derive primarily from the cortical hemisphere contralateral to a moving limb, substantial cortical activations also occur in the same-sided, or ipsilateral, cortical hemisphere. These ipsilateral motor activations have recently been shown to be useful to decode specific movement features. Furthermore, in contrast to the classical understanding that unilateral limb movements are solely driven by the contralateral hemisphere, it appears that the ipsilateral hemisphere plays an active and specific role in the planning and execution of voluntary movements. Here we review the movement-related activations observed in the ipsilateral cortical hemisphere, interpret this evidence in light of the potential roles of the ipsilateral hemisphere in the planning and execution of movements, and describe the implications for clinical populations.
虽然人们早就知道，随意运动主要源自与运动肢体相对的大脑皮质半球，但同侧的大脑皮质半球（即对侧大脑皮质半球）也会发生大量皮质激活。最近的研究表明，这些同侧运动激活对于解码特定的运动特征很有用。此外，与单侧肢体运动仅由对侧大脑半球驱动的经典理解相反，同侧大脑半球似乎在计划和执行随意运动中发挥着积极和特定的作用。在这里，我们回顾了同侧大脑皮质半球中观察到的与运动相关的激活，根据同侧大脑半球在运动计划和执行中的潜在作用来解释这些证据，并描述了其对临床人群的影响。
