Kimura A, Orn A, Holmquist G, Wigzell H, Ersson B
Eur J Immunol. 1979 Jul;9(7):575-8. doi: 10.1002/eji.1830090715.
Cytotoxic T lymphocytes (CTL) can be selectively depleted from in vitro of in vivo alloactivated populations of T cells on Vicia villosa lectin adsorbents through the lectin-specific interaction with the CTL-associated surface glycoprotein T 145 (Kimura, A, Wigzell, H. and Holmquist, G., J. Exp. Med. 1979. 149: 473). Results from these and other experiments have demonstrated the general applicability of this fractionation procedure in which no constraints related to antigenic specificity of the CTL have been observed. When this fractionation procedure was applied to other compartments of cytolytic cells (natural killer cells and "K" cells), no detectable impact could be seen. This differential lectin binding would appear to offer a means of dissecting the activities of CTL from other compartments of cytolytic lymphoid cells.
细胞毒性T淋巴细胞（CTL）可通过与CTL相关表面糖蛋白T 145的凝集素特异性相互作用，在体外或体内从野豌豆凝集素吸附剂上的同种异体激活T细胞群体中被选择性去除（木村，A，维格泽尔，H.和霍尔姆奎斯特，G.，《实验医学杂志》，1979年。149:473）。这些实验和其他实验的结果表明了这种分级分离程序的普遍适用性，在此过程中未观察到与CTL抗原特异性相关的限制。当这种分级分离程序应用于细胞溶解细胞的其他亚群（自然杀伤细胞和“K”细胞）时，未发现可检测到的影响。这种不同的凝集素结合似乎提供了一种从细胞溶解淋巴细胞的其他亚群中剖析CTL活性的方法。
