Department of Pathology, University of Illinois at Chicago, Chicago, Illinois.
Int Wound J. 2019 Dec;16(6):1445-1449. doi: 10.1111/iwj.13212. Epub 2019 Sep 18.
Amelanotic melanoma is a rare melanoma subtype, and it is even more rare when it occurs at an acral site. We here present a case of a nodular amelanotic acral melanoma (NAAM) occurring on the heel of an 83-year old female. It presented as an ulcerated pink nodular growth on the heel, which clinically mimicked other nodular non-pigmented lesions, causing a delay in diagnosis until it was biopsied. This case is a demonstration of the critical importance to include NAAM in the differential diagnosis of nodular non-pigmented skin lesions as to avoid delay in diagnosis and disease progression, in which early detection can provide the most modifiable prognostic factor.
无黑色素性黑色素瘤是一种罕见的黑色素瘤亚型，而发生在肢端部位则更为罕见。我们在此报告一例发生在 83 岁女性足跟部的结节性无黑色素性肢端黑色素瘤（NAAM）。它表现为足跟部溃疡性粉红色结节性生长，临床上类似于其他结节性非色素性病变，导致诊断延迟，直到进行活检。本例病例表明，在鉴别诊断结节性非色素性皮肤病变时，将 NAAM 纳入鉴别诊断至关重要，以避免诊断和疾病进展的延误，早期发现可以提供最具可改变的预后因素。
