Deng Wei, Yu Ruixing, Cui Yong, Zheng Zhancai
Department of Dermatology and Venereology, China-Japan Friendship Hospital, Beijing, China.
An Bras Dermatol. 2019 Jan-Feb;94(1):86-88. doi: 10.1590/abd1806-4841.20197568.
We report a case of amelanotic acral melanoma in a 42-year-old Chinese woman. Ten months previously the patient found a 2-cm asymmetric erythematous macular plaque on her left sole. The lesion was diagnosed as verruca plantaris by every physician the patient consulted. One month ago, an enlarged lymph node was detected in the left groin, which biopsy reported as metastatic melanoma. Dermoscopy suggested verruca plantaris, and positron emission tomography (PET) revealed increased glucose metabolism in the macular plaque. Finally, biopsy of the plaque revealed amelanotic melanoma. Misdiagnosis and diagnostic delay are usually associated with poorer patient outcomes. Awareness of atypical presentations of acral melanoma is thus important for decreasing misdiagnosis rates and improving patient outcomes.
我们报告一例42岁中国女性的无色素性肢端黑色素瘤病例。10个月前，患者在其左脚底发现一个2厘米大小的不对称红斑性斑片。该患者咨询的每位医生均将该病变诊断为跖疣。1个月前，在左腹股沟发现一个肿大淋巴结，活检报告为转移性黑色素瘤。皮肤镜检查提示为跖疣，而正电子发射断层扫描（PET）显示该斑片处葡萄糖代谢增加。最终，该斑片活检显示为无色素性黑色素瘤。误诊和诊断延迟通常与患者预后较差相关。因此，认识肢端黑色素瘤的非典型表现对于降低误诊率和改善患者预后很重要。
