Ko K W, Ha I S, Jin D K, Cheong H I, Choi Y, Kim Y I, Lee H S
Department of Paediatrics, College of Medicine, Seoul National University, Korea.
Pediatr Nephrol. 1987 Oct;1(4):664-9. doi: 10.1007/BF00853605.
Between June 1975 and March 1987, 662 renal biopsies were performed in 657 children at Seoul National University Children's Hospital. Nephrotic syndrome was the most indication for renal biopsy and accounted for 62% of all cases. Of these, 57% showed minimal change lesions and 21% showed focal segmental glomerular sclerosis. Nephropathy, associated with Australia-antigen-positive hepatitis, was the most prominent cause of secondary nephrotic syndrome, and of these patients membranous nephropathy was found in 86%. Diffuse proliferative glomerulonephritis was found in 60% of patients with acute nephritic syndrome. Fifty-eight percent of children with haematuria were found to have either IgA nephropathy or Henoch-Schönlein nephritis. Fifteen children with acute renal failure were biopsied, 2 of whom had haemorrhagic fever.
1975年6月至1987年3月期间，首尔国立大学儿童医院对657名儿童进行了662例肾活检。肾病综合征是肾活检最主要的指征，占所有病例的62%。其中，57%表现为微小病变，21%表现为局灶节段性肾小球硬化。与澳大利亚抗原阳性肝炎相关的肾病是继发性肾病综合征最主要的病因，在这些患者中，86%被发现为膜性肾病。60%的急性肾炎综合征患者被发现患有弥漫性增生性肾小球肾炎。58%的血尿患儿被发现患有IgA肾病或过敏性紫癜性肾炎。对15名急性肾衰竭患儿进行了活检，其中2名患有出血热。
