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对腹腔镜袖状胃切除术后的体重减轻设定现实的期望。

Setting realistic expectations for weight loss after laparoscopic sleeve gastrectomy.

作者信息

Janik Michal R, Rogula Tomasz G, Mustafa Rami R, Saleh Adel Alhaj, Abbas Mujjahid, Khaitan Leena

机构信息

Department of General, Oncologic, Metabolic and Thoracic Surgery, Military Institute of Medicine, Warsaw, Poland.

University Hospital Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, USA.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2019 Sep;14(3):415-419. doi: 10.5114/wiitm.2019.81661. Epub 2019 Jan 22.

Abstract

INTRODUCTION

Despite the clinical benefits of bariatric surgery, some patients have experienced disappointment with their weight loss. Setting realistic expectations is the key to success.

AIM

To develop a specific prediction calculator to estimate the expected body mass index (BMI) at 1 year after laparoscopic sleeve gastrectomy (LSG).

MATERIAL AND METHODS

A retrospective analysis was performed to study 211 patients after primary LSG. Nine baseline variables were analyzed. Least angle regression (LARS) was employed for variable selection and to build the predictive model. External validation was performed on a dataset of 184 patients. To test the accuracy of the model, a Wilcoxon signed-rank test was performed between BMI estimates and the observed BMI. A linear logistic equation was used to construct the online predictive calculator.

RESULTS

The model included three variables - preoperative BMI (β = 0.023, p < 0.001), age (β = 0.005, p < 0.001), and female gender (β = 0.116, p = 0.001) - and demonstrated good discrimination (R = 0.672; adjusted R = 0.664) and good accuracy (root mean squared error of estimate, RMSE = 0.124). The difference between the observed BMI and the estimated BMI was not statistically significant (median = 0.737 (-2.676, 3.254); p = 0.223). External validation confirmed good performance of the model.

CONCLUSIONS

The study revealed a useful predictive model for estimating BMI at 1 year after LSG. The model was used for development of the PREDICT BMI calculator. This tool allows one to set realistic expectations of weight loss at one year after LSG.

摘要

引言

尽管减肥手术具有临床益处,但一些患者对其体重减轻效果感到失望。设定现实的期望是成功的关键。

目的

开发一种特定的预测计算器,以估计腹腔镜袖状胃切除术(LSG)后1年的预期体重指数(BMI)。

材料与方法

对211例行初次LSG的患者进行回顾性分析。分析了9个基线变量。采用最小角回归(LARS)进行变量选择并建立预测模型。在184例患者的数据集中进行外部验证。为检验模型的准确性,在BMI估计值与观察到的BMI之间进行Wilcoxon符号秩检验。使用线性逻辑方程构建在线预测计算器。

结果

该模型包括三个变量——术前BMI(β = 0.023,p < 0.001)、年龄(β = 0.005,p < 0.001)和女性性别(β = 0.116,p = 0.001)——并显示出良好的区分度(R = 0.672;调整后R = 0.664)和良好的准确性(估计均方根误差,RMSE = 0.124)。观察到的BMI与估计的BMI之间的差异无统计学意义(中位数 = 0.737(-2.676,3.254);p = 0.223)。外部验证证实了该模型的良好性能。

结论

该研究揭示了一种用于估计LSG后1年BMI的有用预测模型。该模型用于开发PREDICT BMI计算器。这个工具可以让人们对LSG后1年的体重减轻设定现实的期望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f257/6748060/0ace03ba240e/WIITM-14-34914-g001.jpg

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