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基层医疗中的体位性直立性心动过速综合征:诊断、治疗及一例患体位性直立性心动过速综合征的非裔美国男性病例

Postural orthostatic tachycardia syndrome in primary care: diagnosis, treatment and a case of African-American man presenting with POTS.

作者信息

Del Pozzi Andrew T, Enechukwu Michael, Blitshteyn Svetlana

机构信息

Department of Kinesiology, Ball State University, Muncie, Indiana, USA.

Department of Medicine, State University of New York Upstate Medical University College of Medicine, Syracuse, New York, USA.

出版信息

BMJ Case Rep. 2019 Sep 18;12(9):e229824. doi: 10.1136/bcr-2019-229824.

Abstract

Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous autonomic disorder characterised by orthostatic intolerance and a rise in heart rate by at least 30 bpm or an absolute heart rate value of at least 120 bpm within 10 min of standing or during a tilt table test. Overwhelmingly, POTS affects young Caucasian women, which can lead physicians to miss the diagnosis in men or non-white patients. We describe a case of 29-year-old African-American man who developed lightheadedness, generalised weakness, tachycardia and palpitations and was subsequently diagnosed with POTS. We review its clinical features, differential diagnosis, pathophysiology and treatment options. We also emphasise that POTS should be considered as a differential diagnosis in any patient presenting with typical clinical features, who may not be in the usual demographics of the disorder.

摘要

体位性直立性心动过速综合征(POTS)是一种异质性自主神经功能障碍,其特征为直立不耐受,且在站立10分钟内或倾斜试验期间心率至少增加30次/分钟或绝对心率值至少达到120次/分钟。绝大多数情况下,POTS影响年轻的白人女性,这可能导致医生漏诊男性或非白人患者。我们描述了一名29岁非裔美国男性的病例,他出现了头晕、全身乏力、心动过速和心悸,随后被诊断为POTS。我们回顾了其临床特征、鉴别诊断、病理生理学和治疗选择。我们还强调,对于任何出现典型临床特征的患者,无论其是否符合该疾病的常见人口统计学特征,都应将POTS视为鉴别诊断之一。

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本文引用的文献

1
Exercise and non-pharmacological treatment of POTS.运动和非药物治疗 POTS。
Auton Neurosci. 2018 Dec;215:20-27. doi: 10.1016/j.autneu.2018.07.001. Epub 2018 Jul 4.
5
Pharmacotherapy for postural tachycardia syndrome.体位性心动过速综合征的药物治疗。
Auton Neurosci. 2018 Dec;215:28-36. doi: 10.1016/j.autneu.2018.04.008. Epub 2018 May 4.
6
Cognitive and psychological issues in postural tachycardia syndrome.姿势性心动过速综合征的认知和心理问题。
Auton Neurosci. 2018 Dec;215:46-55. doi: 10.1016/j.autneu.2018.03.004. Epub 2018 Mar 27.

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