Barua Mousumi
Internal Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, USA.
Cureus. 2024 Oct 16;16(10):e71606. doi: 10.7759/cureus.71606. eCollection 2024 Oct.
Postural orthostatic tachycardia syndrome (POTS) often manifests following an acute infection. This case study reports a post-malarial onset of POTS in a young female medical student who presented with tachycardia, dizziness, presyncope, several episodes of syncope, and dysautonomic symptoms. The diagnosis of POTS was established only four years later by a tilt table test. The patient made a remarkable functional recovery from POTS, as she responded well to pharmacotherapy, primarily beta-blockers, along with lifestyle modifications. Although mild dysautonomic symptoms such as lack of thermoregulation and decreased perspiration have persisted throughout her life, the patient has managed to cope with these symptoms and function well in her daily life. To our knowledge, this is probably the first reported case of post-malarial POTS, and we recommend that the non-viral etiology of POTS, particularly the post-malarial cases, be studied in detail to understand the pathophysiology and management of this disorder.
体位性直立性心动过速综合征（POTS）常于急性感染后出现。本病例研究报告了一名年轻女医学生在疟疾发作后出现POTS，表现为心动过速、头晕、先兆晕厥、多次晕厥发作以及自主神经功能障碍症状。POTS的诊断直到四年后通过倾斜试验才得以确立。患者对药物治疗（主要是β受体阻滞剂）以及生活方式的改变反应良好，从POTS中实现了显著的功能恢复。尽管诸如体温调节缺失和出汗减少等轻度自主神经功能障碍症状在她一生中持续存在，但患者已设法应对这些症状并在日常生活中功能良好。据我们所知，这可能是首例报告的疟疾后POTS病例，我们建议对POTS的非病毒病因，特别是疟疾后病例进行详细研究，以了解该疾病的病理生理学和管理方法。
