老年患者的胃食管反流病:临床表现、治疗及并发症

Gastroesophageal reflux disease in the older patient: presentation, treatment, and complications.

作者信息

Richter J E

机构信息

Department of Gastroenterology, Cleveland Clinic Foundation, Ohio 44195, USA.

出版信息

Am J Gastroenterol. 2000 Feb;95(2):368-73. doi: 10.1111/j.1572-0241.2000.t01-1-01791.x.

Abstract

Gastroesophageal reflux disease (GERD) is common in the elderly. Patients often complain of less severe or frequent heartburn than their younger cohorts, but because of prolonged acid exposure over many years, the elderly have more complicated reflux disease including esophagitis, peptic strictures, and Barrett's esophagus. Potential factors aggravating GERD in the elderly include medications, which reduce lower esophageal sphincter pressure, higher frequency of hiatal hernia, impaired motility, and decreased saliva volume and bicarbonate concentration. Early endoscopy is indicated in all elderly patients with GERD, regardless of symptom severity. The medical and surgical treatment of GERD in the elderly generally follows the same principles as for any adult patient.

摘要

胃食管反流病(GERD)在老年人中很常见。与年轻患者相比,老年患者经常抱怨烧心症状不那么严重或发作频率较低,但由于多年来胃酸暴露时间延长,老年患者的反流病更为复杂,包括食管炎、消化性狭窄和巴雷特食管。加重老年人GERD的潜在因素包括降低食管下括约肌压力的药物、食管裂孔疝发生率较高、运动功能受损以及唾液量和碳酸氢盐浓度降低。所有GERD老年患者,无论症状严重程度如何,均需尽早进行内镜检查。老年人GERD的药物和手术治疗一般遵循与成年患者相同的原则。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索