Hong K S, Kim S Y, Koo W S, Choi E J, Cha B Y, Chang Y S, Yoon Y S, Son H Y, Bang B K
Korean J Intern Med. 1988 Jul;3(2):117-21. doi: 10.3904/kjim.1988.3.2.117.
Using urinary microalbumin radioimmunoassay, we evaluated the clinical utility of microalbumin excretion in nephrotic syndrome with complete remission, isolated microscopic hematuria and kidney donors in reanl transplantation. The highest value in normal controls was 10.86 μg/min, and the upper normal level was set to 15 μg/min. The range of microalbuminuria in patients with nephrotic syndrome with complete remission was 1.67 μg/min to 32.5 μg/min. There was no significant correlation between the recurrence rate and microlbuminuria level in nephrotic syndrome with complete remission. The range of microalbuminuria levels in isolated microscopic hematuric patients was between 2.37μg/min and 103.2 μg/min. There was no singificant correlation between the amount of the red blood cells in urine and the level of microalbuminuria in the isolated microscopic hematuric patients. Most renal transplantation donors showed a normal range of microalbuminuria after nephrectomy. The aim of this study was to evaluate the clinical utility of urinary microalbuminuria in diseases other than diabetes. We concluded that further extensive and specific study will be required to determine the clinical utility of microalbuminuria.
我们采用尿微量白蛋白放射免疫分析法，评估了微量白蛋白排泄在完全缓解的肾病综合征、孤立性镜下血尿以及肾移植供体中的临床应用价值。正常对照组的最高值为10.86μg/分钟，正常上限设定为15μg/分钟。完全缓解的肾病综合征患者的微量白蛋白尿范围为1.67μg/分钟至32.5μg/分钟。完全缓解的肾病综合征患者的复发率与微量白蛋白尿水平之间无显著相关性。孤立性镜下血尿患者的微量白蛋白尿水平范围在2.37μg/分钟至103.2μg/分钟之间。孤立性镜下血尿患者尿中红细胞数量与微量白蛋白尿水平之间无显著相关性。大多数肾移植供体在肾切除术后微量白蛋白尿范围正常。本研究的目的是评估尿微量白蛋白尿在糖尿病以外疾病中的临床应用价值。我们得出结论，需要进一步进行广泛而具体的研究以确定微量白蛋白尿的临床应用价值。
