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SSRIs 停药后性功能障碍和其他持续性性功能障碍。

Post-SSRI sexual dysfunction & other enduring sexual dysfunctions.

机构信息

Bangor University, Psychiatry, Bangor, Gwynedd, UK.

出版信息

Epidemiol Psychiatr Sci. 2019 Sep 23;29:e55. doi: 10.1017/S2045796019000519.

DOI:10.1017/S2045796019000519
PMID:31543091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8061302/
Abstract

Enduring sexual difficulties following treatment with selective serotonin reuptake inhibitor antidepressants have been reported to regulators since 1991, but it was only in 2006 that a formal post-SSRI sexual dysfunction syndrome was reported. The clinical, research and regulatory implications of this syndrome are considerable and researchers using epidemiological methods are well placed to map out the contours of the problem and perhaps pinpoint possible treatments.

摘要

自 1991 年以来,监管机构就收到了关于使用选择性 5-羟色胺再摄取抑制剂(SSRIs)类抗抑郁药治疗后仍存在性困难的报告,但直到 2006 年才正式报告了 SSRIs 类药物引起的性功能障碍综合征。该综合征在临床、研究和监管方面都具有重要意义,使用流行病学方法的研究人员能够很好地描绘出问题的轮廓,并可能确定可能的治疗方法。

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Soc Psychiatry Psychiatr Epidemiol. 2024 Sep 20. doi: 10.1007/s00127-024-02769-0.
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Medicines (Basel). 2022 Sep 1;9(9):45. doi: 10.3390/medicines9090045.
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本文引用的文献

1
Citizen petition: Sexual side effects of SSRIs and SNRIs.公民请愿书:选择性5-羟色胺再摄取抑制剂(SSRI)和5-羟色胺-去甲肾上腺素再摄取抑制剂(SNRI)的性副作用
Int J Risk Saf Med. 2018;29(3-4):135-147. doi: 10.3233/JRS-180745.
2
Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases.使用抗抑郁药、5α-还原酶抑制剂和异维A酸治疗后出现的持续性性功能障碍:300例病例。
Int J Risk Saf Med. 2018;29(3-4):125-134. doi: 10.3233/JRS-180744.
3
Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.药物诱导的长QT综合征的晚钠电流阻滞:一项前瞻性临床试验的结果。
Clin Pharmacol Ther. 2016 Feb;99(2):214-23. doi: 10.1002/cpt.205. Epub 2015 Nov 28.
4
One hundred and twenty cases of enduring sexual dysfunction following treatment.治疗后出现持续性性功能障碍120例。
Int J Risk Saf Med. 2014;26(2):109-16. doi: 10.3233/JRS-140617.
5
Persistent sexual side effects of finasteride for male pattern hair loss.非那雄胺治疗男性型脱发的持续性性副作用。
J Sex Med. 2011 Jun;8(6):1747-53. doi: 10.1111/j.1743-6109.2011.02255.x. Epub 2011 Mar 18.
6
Block of persistent late Na+ currents by antidepressant sertraline and paroxetine.抗抑郁药舍曲林和帕罗西汀对持续性晚钠电流的阻断作用。
J Membr Biol. 2008 Mar;222(2):79-90. doi: 10.1007/s00232-008-9103-y. Epub 2008 Apr 17.
7
Persistent sexual side effects after SSRI discontinuation.
Psychother Psychosom. 2006;75(3):187-8. doi: 10.1159/000091777.
8
Persistent sexual arousal syndrome: a newly discovered pattern of female sexuality.持续性性唤起综合征:一种新发现的女性性行为模式。
J Sex Marital Ther. 2001 Jul-Sep;27(4):365-80. doi: 10.1080/009262301317081115.
9
Pharmacological stress diathesis syndromes.
J Psychopharmacol. 1999;13(3):287-90. doi: 10.1177/026988119901300312.