Suppr超能文献

表现为银屑病样皮损的穿通性环状肉芽肿

Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion.

作者信息

Witkoff Benjamin M, Ivanov Nedyalko N, Trotter Shannon C

机构信息

Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio, USA.

Private Practice Oakview Dermatology, Springfield, Ohio, USA.

出版信息

Case Rep Dermatol. 2019 Aug 6;11(2):233-238. doi: 10.1159/000501875. eCollection 2019 May-Aug.

Abstract

We present a 54-year-old Caucasian female with a history of diabetes mellitus, multiple sclerosis, and ulcerative colitis who presented with nail dystrophy, polyarthralgia in her hands and hips, myalgia, proximal myopathy, dactylitis, and psoriasiform-appearing progressive, painful plaques on the dorsal aspect of her hands. Histologic examination of the lesion from the left index finger revealed an interstitial and necrobiotic granulomatous dermatitis with connective tissue mucin deposition associated with a perivascular lymphoid infiltrate. Additionally, there was focal transepidermal elimination of the necrobiotic material. She was diagnosed with perforating granuloma annulare (PGA). We are unaware of any other cases of PGA in the literature with this presentation.

摘要

我们报告一名54岁的白种女性,有糖尿病、多发性硬化症和溃疡性结肠炎病史,出现了甲营养不良、手部和髋部多关节痛、肌痛、近端肌病、指(趾)炎以及手部背侧出现银屑病样外观的进行性疼痛斑块。对左手食指病变进行组织学检查,显示为间质性和坏死性肉芽肿性皮炎,伴有结缔组织黏蛋白沉积,并有血管周围淋巴细胞浸润。此外,有坏死物质的局灶性经表皮排出。她被诊断为穿通性环状肉芽肿(PGA)。我们未在文献中发现有此表现的其他PGA病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cc7/6738183/4dab940dbf7d/cde-0011-0233-g01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验