Department of Dermatology and Venereology, Hospital Garcia de Orta, Av. Torrado da Silva, 2801-951 Almada, Portugal.
Healthcare (Basel). 2014 Sep 4;2(3):338-45. doi: 10.3390/healthcare2030338.
Perforating granuloma annulare (GA) is a rare subset of GA with an unknown etiology and chronic course. Herein, we report the case of 72 year-old women with a 3-month history of a post-traumatic, persistent, erythematous and exudative plaque located on her left leg. Differential diagnosis included mycobacterial infection, subcutaneous mycosis, perforating dermatoses, pyoderma and squamous cell carcinoma. The histopathology was highly suggestive of a perforating GA. The patient was treated with betamethasone dipropionate cream applied once daily and a complete resolution of the lesion was observed in three weeks. Despite being a very rare subtype of a common disease, perforating granuloma annulare has clinical and histopathological characteristic features that facilitate the differential diagnosis, avoiding unnecessary procedures and inadequate and potentially more invasive treatments.
穿通性环状肉芽肿（GA）是 GA 的一种罕见亚型，病因不明，病程慢性。在此，我们报告一例 72 岁女性患者，其左腿有 3 个月外伤性、持续性、红斑和渗出性斑块病史。鉴别诊断包括分枝杆菌感染、皮下真菌感染、穿通性皮肤病、脓疱病和鳞状细胞癌。组织病理学高度提示为穿通性 GA。患者接受倍他米松二丙酸酯乳膏治疗，每日一次，3 周后皮损完全消退。尽管是一种常见疾病的非常罕见亚型，但穿通性环状肉芽肿具有临床和组织病理学特征，有助于鉴别诊断，避免不必要的检查和不适当的、潜在更具侵袭性的治疗。
