Isolation of in the saliva samples of patient candidates for liver transplantation.

BACKGROUND

Liver transplantation has turn into a standard management for chronic liver failure (CLF), and the number of recipients increased during the last few years. Enterococci are progressively related to nosocomial and opportunistic infections. Oral cavity may act as a reservoir for this species, especially in cases with oral infection. Immunocompromised patients are prone to serious enterococci-related disease. This study investigated the prevalence of in the saliva samples of patient candidates for liver transplantation.

MATERIALS AND METHODS

In this cross-sectional study the saliva samples of 100 patient candidates for liver transplantation and 100 age- and sex-matched healthy control group were collected. Bacterial DNA was extracted from the samples and was detected using polymerase chain reaction test. Fisher's exact test and Mann-Whitney test were used to correlate the positive and negative cases with the disease. Statistically, a significant difference was considered when < 0.05.

RESULTS

There was no significant difference between both groups for the presence of . This bacterium isolated from the saliva of two cases in the study group and only one healthy control. The higher rate of carious teeth were detected in the oral cavity of CLF cases than control group ( = 0.001).

CONCLUSION

Patients with chronic liver diseases assessed in this research showed a higher incidence of poor oral health and caries compared with the healthy controls, but there was no statistical difference in the presence of in saliva samples of each group. Complete oral examination, dental treatment, and oral hygiene instruction are necessary for all these cases before liver transplantation.