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老矿区居民血汞浓度与高血压的关系及相关因素研究

A study of relationship between blood mercury concentration and hypertension in residents living in old mine fields and related factors.

作者信息

Kim Jeong Woo, Kim Byoung Gwon, Park Jeong Woo, Yi Jong Woo, Kim Jung Il, Hong Young Seoub

机构信息

Department of Occupational and Environmental Medicine, College of Medicine, Dong-A University, Busan, Korea.

Heavy Metal Exposure Environmental Health Center, Dong-A University, Busan, Korea.

出版信息

Ann Occup Environ Med. 2019 May 30;31:e6. doi: 10.35371/aoem.2019.31.e6. eCollection 2019.

Abstract

BACKGROUND

In Korea, around the abandoned metal mines, heavy metals are being accumulating in the cultivated areas. Among exposed heavy metals, mercury is known to harm for cardiovascular system known to affect blood pressure. So, we studied the relationship between blood mercury level and hypertension in residents around abandoned metal mines.

METHODS

From 2008 to 2011, we surveyed 7,055 residents in provinces affected by abandoned metal mines and collected data from 6 Hospitals. We conducted a personal questionnaire interview survey with residents on the basis of household questionnaires, sex, age, household income, smoking, and drinking items. Multiple logistic regression analysis was performed to investigate the association between blood mercury level and hypertension.

RESULTS

We compared residents with low and high groups based on blood mercury level 5.8 μg/L, and higher group was significantly higher risk of hypertension than lower group (odds ratio [OR]: 1.277; 95% confidence interval [CI]: 1.135-1.436), also in adjusted model, higher group was significantly higher risk of hypertension than lower group (OR: 1.276; 95% CI: 1.117-1.457).

CONCLUSIONS

This study showed a significant correlation between mercury and hypertension in residents around abandoned metal mines. Therefore, we should continuously monitor people who are higher than the standard value and the hypertensive patients.

摘要

背景

在韩国,废弃金属矿周围的耕地区域重金属正在不断累积。在暴露的重金属中,汞已知会损害心血管系统,进而影响血压。因此,我们研究了废弃金属矿周围居民的血汞水平与高血压之间的关系。

方法

2008年至2011年,我们对受废弃金属矿影响省份的7055名居民进行了调查,并从6家医院收集了数据。我们在家庭问卷的基础上,就性别、年龄、家庭收入、吸烟和饮酒情况对居民进行了个人问卷调查访谈。进行多因素逻辑回归分析以研究血汞水平与高血压之间的关联。

结果

我们根据血汞水平5.8μg/L将居民分为低水平组和高水平组进行比较,高水平组患高血压的风险显著高于低水平组(优势比[OR]:1.277;95%置信区间[CI]:1.135 - 1.436),在调整模型中,高水平组患高血压的风险也显著高于低水平组(OR:1.276;95%CI:1.117 - 1.457)。

结论

本研究表明废弃金属矿周围居民的汞与高血压之间存在显著相关性。因此,我们应持续监测高于标准值的人群以及高血压患者。

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The German Human Biomonitoring Commission.德国人体生物监测委员会。
Int J Hyg Environ Health. 2007 May;210(3-4):373-82. doi: 10.1016/j.ijheh.2007.01.035. Epub 2007 Mar 6.

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