Nirmal Balakrishnan, Krishnaram Ananthu Subbaraman, Muthu Yegu, Rajagopal Poongodi
Department of Dermatology, Velammal Medical College and Research Institute, Madurai, Tamil Nadu, India.
Department of Pathology, Velammal Medical College and Research Institute, Madurai, Tamil Nadu, India.
Indian Dermatol Online J. 2019 Aug 28;10(5):577-579. doi: 10.4103/idoj.IDOJ_501_18. eCollection 2019 Sep-Oct.
Urticaria pigmentosa is the most common form of mastocytosis that often develops in infancy or early childhood. We report two male children- first, a 7-month-old child with a history of asymptomatic multiple dark colored skin lesions macules with wheals on gentle rubbing (Darier's sign) and second, a 2-year-old child with similar clinical presentation without Darier's sign. Dermoscopy showed dark brown lines in a reticulate pattern which is an exaggeration of the pigment network seen in the normal skin. The reticulate pigment network was darker and thicker in the child with positive Darier's sign. This is the first case report of dermoscopy of urticarial pigmentosa with and without Darier's sign reported in skin of colour.
色素性荨麻疹是肥大细胞增多症最常见的形式，常于婴儿期或幼儿期发病。我们报告两名男童——第一名是一名7个月大的儿童，有多个无症状深色皮肤损害斑疹病史，轻擦后出现风团（达里埃氏征）；第二名是一名2岁儿童，临床表现相似但无达里埃氏征。皮肤镜检查显示呈网状分布的深棕色线条，这是正常皮肤中所见色素网的一种夸张表现。有阳性达里埃氏征的儿童其网状色素网更暗、更厚。这是首例关于有色人种皮肤中伴有和不伴有达里埃氏征的色素性荨麻疹皮肤镜检查的病例报告。
