Akay Bengü Nisa, Kittler Harald, Sanli Hatice, Harmankaya Kaan, Anadolu Rana
Department of Dermatology, Ankara University School of Medicine, Ankara, Turkey.
Dermatology. 2009;218(3):226-30. doi: 10.1159/000182260. Epub 2008 Dec 6.
Mastocytosis is a disorder characterized by the accumulation of mast cells in various organs, most commonly in the skin. Cutaneous mastocytosis (CM) can be classified as nodular CM with solitary or multiple lesions, diffuse CM (erythroderma), and maculopapular CM including the papular/plaque variant, urticaria pigmentosa (UP) and telangiectasia macularis eruptiva perstans (TMEP).
To evaluate the dermatoscopic features of cutaneous mastocytosis.
We reviewed the dermatoscopic images of 6 patients who had different variants of cutaneous mastocytosis and who attended the Departments of Dermatology at the Medical University of Ankara, Turkey, and the Medical University of Vienna, Austria.
In UP and in the papular variant of CM the most common structures seen by dermatoscopy were brown reticular lines (pigment network). In TMEP we observed telangiectatic vessels arranged in a reticular pattern.
Skin lesions of mastocytosis may exhibit a pigment network, a dermatoscopic feature said to be characteristic of melanocytic lesions. We were also able to identify a new dermatoscopic feature, a reticular vascular pattern that is characteristic of a clinical variant of mastocytosis known as TMEP. This feature may help to differentiate TMEP from other variants of mastocytosis and from other exanthematous skin diseases.
肥大细胞增多症是一种以肥大细胞在各个器官(最常见于皮肤)中积聚为特征的疾病。皮肤肥大细胞增多症(CM)可分为具有单个或多个病变的结节性CM、弥漫性CM(红皮病)以及斑丘疹性CM,包括丘疹/斑块型、色素性荨麻疹(UP)和持久性斑疹性血管扩张症(TMEP)。
评估皮肤肥大细胞增多症的皮肤镜特征。
我们回顾了6例患有不同类型皮肤肥大细胞增多症的患者的皮肤镜图像,这些患者分别就诊于土耳其安卡拉医科大学和奥地利维也纳医科大学的皮肤科。
在色素性荨麻疹以及CM的丘疹型中,皮肤镜检查所见的最常见结构是棕色网状线(色素网)。在持久性斑疹性血管扩张症中,我们观察到呈网状排列的毛细血管扩张。
肥大细胞增多症的皮肤病变可能表现出色素网,这是一种据说是黑素细胞性病变特征性的皮肤镜特征。我们还能够识别一种新的皮肤镜特征,即网状血管模式,这是肥大细胞增多症的一种临床类型——持久性斑疹性血管扩张症的特征。这一特征可能有助于将持久性斑疹性血管扩张症与肥大细胞增多症的其他类型以及其他发疹性皮肤病区分开来。