Paparizos Vassilios, Vasalou Varvara, Velissariou Eirini, Kourkounti Sofia, Daskalakis Evangelos, Rigopoulos Dimitrios
HIV/AIDS Unit, "Andreas Sygros" Hospital, Athens, Greece.
Department of Dermatology and Venereology, Andreas Sygros Hospital, Athens, Greece.
Infez Med. 2019 Sep 1;27(3):332-335.
Crusted scabies is a rare and extreme manifestation of scabies that is observed mainly among immunosuppressed patients. We describe the case of a 55-year-old patient with a history of HIV infection and injection drug use. The patient was not on any antiretroviral therapy during the previous year, was malnourished and was living in unsanitary conditions. He had extensive, generalized, thick, hyperkeratotic, crusting, papular lesions, which had evolved over the previous month. Hyperkeratotic areas were fissured and linear excoriations were noted diffusely. The rash was distributed on the entire body from the scalp to the toes, with mild itching. Microscopic examination of the scale revealed numerous scabies mites and eggs. The patient was treated with topical scabicidal agents, which resulted in complete resolution. Because of the extremely contagious nature of crusted scabies, as well as its potential for complete cure with an appropriate therapy, there should be a high degree of suspicion for this disease in patients with AIDS, even when the lesions do not have the classical appearance. Nosocomial transmission of scabies from patients with AIDS is a risk, and protective measures, early diagnosis, and therapy are essential.
结痂性疥疮是疥疮的一种罕见且严重的表现形式,主要见于免疫抑制患者。我们描述了一例55岁有HIV感染和注射吸毒史的患者。该患者前一年未接受任何抗逆转录病毒治疗,营养不良,生活在不卫生的环境中。他有广泛、全身性、增厚、角化过度、结痂的丘疹性皮损,这些皮损在过去一个月内逐渐发展。角化过度区域有裂隙,全身可见散在的线状抓痕。皮疹从头皮到脚趾遍布全身,伴有轻度瘙痒。对鳞屑进行显微镜检查发现大量疥螨和虫卵。患者接受了外用杀疥剂治疗,结果完全治愈。由于结痂性疥疮具有极强的传染性,且通过适当治疗有完全治愈的可能,因此即使皮损没有典型表现,对艾滋病患者也应高度怀疑此病。艾滋病患者发生疥疮的医院内传播存在风险,采取保护措施、早期诊断和治疗至关重要。