Talaga-Ćwiertnia Katarzyna
Jagiellonian University Medical College, Faculty of Medicine, Chair of Microbiology, Department of Infection Control and Mycology, 31-008 Kraków, Poland.
Pathogens. 2021 Jul 9;10(7):868. doi: 10.3390/pathogens10070868.
Currently, there are three known subtypes of scabies: ordinary, crusted, and bullous. The worldwide prevalence of scabies remains high in the 21st century. To decrease the social, economic, and psychological impact on the enormous population infected, a lot of important work has been completed over the last 20 years concerning the management of scabies. For example, a standardization of guidelines for the treatment of scabies has been completed and programs have been designed for the prevention and treatment in endemic populations, called mass drug administrations. Unfortunately, these only apply to the ordinary form of scabies. Moreover, resistance to the drugs currently used in treatment is growing, which imposes the need to search for new treatments. For this purpose, new acaricides are being developed to enhance the therapeutic options for the patients' benefit and effectively treat this disease. There is also the necessity for prevention before the development of scabies. An effective vaccine has the potential to protect people before this disease, especially in endemic areas. Unfortunately, there are no such vaccines against yet.
目前，已知疥疮有三种亚型：普通型、结痂型和大疱型。在21世纪，疥疮在全球的患病率仍然很高。为了减少对大量感染者的社会、经济和心理影响，在过去20年里，关于疥疮管理已经完成了许多重要工作。例如，已经完成了疥疮治疗指南的标准化，并为流行地区的预防和治疗设计了项目，即大规模药物给药。不幸的是，这些仅适用于普通型疥疮。此外，目前用于治疗的药物的耐药性正在增加，这就需要寻找新的治疗方法。为此，正在开发新的杀螨剂，以增加治疗选择，造福患者并有效治疗这种疾病。在疥疮发病之前进行预防也很有必要。一种有效的疫苗有可能在这种疾病发生之前保护人们，尤其是在流行地区。不幸的是，目前还没有针对疥疮的此类疫苗。
