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肾移植受者继发于三发性甲状旁腺功能亢进的罕见下颌骨棕色瘤。

Rare brown tumour of the mandible secondary to tertiary hyperparathyroidism in a renal transplant recipient.

作者信息

Guéroult Aurélien M, Cameron Malcolm

机构信息

Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Oral and Maxillofacial Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

出版信息

BMJ Case Rep. 2019 Sep 24;12(9):e231231. doi: 10.1136/bcr-2019-231231.

Abstract

Brown tumours are rare osteolytic lesions that occur secondary to hyperparathyroidism (HPT). In 2% of all cases, the craniofacial bones are affected, most frequently the mandible. HPT is classified according to aetiology into three types, of which tertiary HPT is the rarest. Here we present the case of a 42-year-old man who had received a renal transplant 16 years previously and was referred due to swelling on the right side of his jaw. An orthopantomogram revealed a multilocular radiolucency in the right body of the mandible. The bony lesion was treated by surgical enucleation. After histopathological examination of the lesion, the diagnosis of brown tumour of the mandible secondary to tertiary HPT was reached. The patient's recovery was uneventful and follow-up radiography showed good bone healing.

摘要

棕色瘤是继发于甲状旁腺功能亢进症(HPT)的罕见溶骨性病变。在所有病例中,2%的患者颅面骨会受到影响,最常见的是下颌骨。HPT根据病因分为三种类型,其中三发性HPT最为罕见。在此,我们报告一例42岁男性患者,该患者16年前接受了肾移植,因右侧颌部肿胀前来就诊。曲面体层摄影显示下颌骨右侧体部有一多房性透射区。通过手术摘除对骨病变进行了治疗。对病变进行组织病理学检查后,确诊为三发性HPT继发的下颌骨棕色瘤。患者恢复顺利,随访X线检查显示骨愈合良好。

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