Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Sci Rep. 2019 Sep 24;9(1):13760. doi: 10.1038/s41598-019-50295-w.
This study aimed to explore the combined effects of having sleep problems and taking sleeping pills on the skeletal muscle mass and performance of community-dwelling elders. A total of 826 participants who have complete information regarding dual-energy X-ray absorptiometry examination, questionnaire, and physical performance tests were included. The status of having sleep problems and taking sleeping pills was assessed with a self-reported questionnaire. The prevalence rates of sleep problems among older men and women were 37.4% and 54.5%, respectively. After multivariate adjustment, the mean height-adjusted skeletal muscle indices for elders having sleep problems and taking sleeping pills among men and women were 7.29 and 5.66 kg/m, respectively, which were lower than those without sleep problems (P = 0.0021 and P = 0.0175). The performance of the older men having sleep problems and taking sleeping pills in terms of walking speed, grip strength, and number of squats, was poorer than those of the older men without sleep problems. The status of having sleep problems and taking sleeping pills was correlated with low skeletal muscle mass and poor physical performance in community-dwelling elders. These findings suggest that having sleep problems and taking sleeping pills are associated with having sarcopenia among community elderly.
本研究旨在探讨同时存在睡眠问题和服用助眠药物对社区居住老年人骨骼肌量和身体机能的综合影响。共纳入了 826 名完整信息（包括双能 X 射线吸收仪检查、问卷调查和身体机能测试）的参与者。通过自我报告问卷评估睡眠问题和服用助眠药物的状况。老年人中存在睡眠问题的男性和女性的患病率分别为 37.4%和 54.5%。经多变量调整后，男性和女性中存在睡眠问题和服用助眠药物的老年人的身高调整后骨骼肌指数均值分别为 7.29 和 5.66kg/m，低于无睡眠问题的老年人（P=0.0021 和 P=0.0175）。存在睡眠问题和服用助眠药物的老年男性在行走速度、握力和深蹲次数方面的表现均不如无睡眠问题的老年男性。存在睡眠问题和服用助眠药物的状态与社区居住老年人的骨骼肌量低和身体机能差有关。这些发现表明，社区老年人中存在睡眠问题和服用助眠药物与肌少症有关。
