Carrette Evelien, Stefan Hermann
Reference Centre for Refractory Epilepsy, Ghent University Hospital, Ghent, Belgium.
Department of Neurology-Biomagnetism, University Hospital Erlangen, Erlangen, Germany.
Front Neurol. 2019 Sep 10;10:933. doi: 10.3389/fneur.2019.00933. eCollection 2019.
Magnetoencephalography (MEG) in the field of epilepsy has multiple advantages; just like electroencephalography (EEG), MEG is able to measure the epilepsy specific information (i.e., the brain activity reflecting seizures and/or interictal epileptiform discharges) directly, non-invasively and with a very high temporal resolution (millisecond-range). In addition MEG has a unique sensitivity for tangential sources, resulting in a full picture of the brain activity when combined with EEG. It accurately allows to perform source imaging of focal epileptic activity and functional cortex and shows a specific high sensitivity for a source in the neocortex. In this paper the current evidence and practice for using magnetic source imaging of focal interictal and ictal epileptic activity during the presurgical evaluation of drug resistant patients is being reviewed.
在癫痫领域，脑磁图（MEG）具有多种优势；与脑电图（EEG）一样，MEG能够直接、非侵入性地且以非常高的时间分辨率（毫秒级）测量癫痫特异性信息（即反映癫痫发作和/或发作间期癫痫样放电的脑活动）。此外，MEG对切线源具有独特的敏感性，与EEG结合时可全面呈现脑活动情况。它能够准确地对局灶性癫痫活动和功能皮层进行源成像，并且对新皮层中的源显示出特定的高敏感性。本文将对耐药患者术前评估期间使用局灶性发作间期和发作期癫痫活动磁源成像的当前证据和实践进行综述。
